Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase
The ability to target DNA methylation to specific loci is important for both basic and applied research. Here, the authors fuse CG-specific methyltransferase SssI with an artificial zinc finger protein for DNA methylation targeting and show the chromatin features favorable for efficient gain of meth...
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Nature Portfolio
2021
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oai:doaj.org-article:12a43b312aae4d20bbb35f315282c71a2021-12-02T15:49:30ZEctopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase10.1038/s41467-021-23346-y2041-1723https://doaj.org/article/12a43b312aae4d20bbb35f315282c71a2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23346-yhttps://doaj.org/toc/2041-1723The ability to target DNA methylation to specific loci is important for both basic and applied research. Here, the authors fuse CG-specific methyltransferase SssI with an artificial zinc finger protein for DNA methylation targeting and show the chromatin features favorable for efficient gain of methylation.Wanlu LiuJavier Gallego-BartoloméYuxing ZhouZhenhui ZhongMing WangSomsakul Pop WongpaleeJason GardinerSuhua FengPeggy Hsuanyu KuoSteven E. JacobsenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
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Science Q Wanlu Liu Javier Gallego-Bartolomé Yuxing Zhou Zhenhui Zhong Ming Wang Somsakul Pop Wongpalee Jason Gardiner Suhua Feng Peggy Hsuanyu Kuo Steven E. Jacobsen Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase |
description |
The ability to target DNA methylation to specific loci is important for both basic and applied research. Here, the authors fuse CG-specific methyltransferase SssI with an artificial zinc finger protein for DNA methylation targeting and show the chromatin features favorable for efficient gain of methylation. |
format |
article |
author |
Wanlu Liu Javier Gallego-Bartolomé Yuxing Zhou Zhenhui Zhong Ming Wang Somsakul Pop Wongpalee Jason Gardiner Suhua Feng Peggy Hsuanyu Kuo Steven E. Jacobsen |
author_facet |
Wanlu Liu Javier Gallego-Bartolomé Yuxing Zhou Zhenhui Zhong Ming Wang Somsakul Pop Wongpalee Jason Gardiner Suhua Feng Peggy Hsuanyu Kuo Steven E. Jacobsen |
author_sort |
Wanlu Liu |
title |
Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase |
title_short |
Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase |
title_full |
Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase |
title_fullStr |
Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase |
title_full_unstemmed |
Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase |
title_sort |
ectopic targeting of cg dna methylation in arabidopsis with the bacterial sssi methyltransferase |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/12a43b312aae4d20bbb35f315282c71a |
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