Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase

The ability to target DNA methylation to specific loci is important for both basic and applied research. Here, the authors fuse CG-specific methyltransferase SssI with an artificial zinc finger protein for DNA methylation targeting and show the chromatin features favorable for efficient gain of meth...

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Autores principales: Wanlu Liu, Javier Gallego-Bartolomé, Yuxing Zhou, Zhenhui Zhong, Ming Wang, Somsakul Pop Wongpalee, Jason Gardiner, Suhua Feng, Peggy Hsuanyu Kuo, Steven E. Jacobsen
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/12a43b312aae4d20bbb35f315282c71a
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spelling oai:doaj.org-article:12a43b312aae4d20bbb35f315282c71a2021-12-02T15:49:30ZEctopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase10.1038/s41467-021-23346-y2041-1723https://doaj.org/article/12a43b312aae4d20bbb35f315282c71a2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23346-yhttps://doaj.org/toc/2041-1723The ability to target DNA methylation to specific loci is important for both basic and applied research. Here, the authors fuse CG-specific methyltransferase SssI with an artificial zinc finger protein for DNA methylation targeting and show the chromatin features favorable for efficient gain of methylation.Wanlu LiuJavier Gallego-BartoloméYuxing ZhouZhenhui ZhongMing WangSomsakul Pop WongpaleeJason GardinerSuhua FengPeggy Hsuanyu KuoSteven E. JacobsenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Wanlu Liu
Javier Gallego-Bartolomé
Yuxing Zhou
Zhenhui Zhong
Ming Wang
Somsakul Pop Wongpalee
Jason Gardiner
Suhua Feng
Peggy Hsuanyu Kuo
Steven E. Jacobsen
Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase
description The ability to target DNA methylation to specific loci is important for both basic and applied research. Here, the authors fuse CG-specific methyltransferase SssI with an artificial zinc finger protein for DNA methylation targeting and show the chromatin features favorable for efficient gain of methylation.
format article
author Wanlu Liu
Javier Gallego-Bartolomé
Yuxing Zhou
Zhenhui Zhong
Ming Wang
Somsakul Pop Wongpalee
Jason Gardiner
Suhua Feng
Peggy Hsuanyu Kuo
Steven E. Jacobsen
author_facet Wanlu Liu
Javier Gallego-Bartolomé
Yuxing Zhou
Zhenhui Zhong
Ming Wang
Somsakul Pop Wongpalee
Jason Gardiner
Suhua Feng
Peggy Hsuanyu Kuo
Steven E. Jacobsen
author_sort Wanlu Liu
title Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase
title_short Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase
title_full Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase
title_fullStr Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase
title_full_unstemmed Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase
title_sort ectopic targeting of cg dna methylation in arabidopsis with the bacterial sssi methyltransferase
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/12a43b312aae4d20bbb35f315282c71a
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