An evolutionary-network model reveals stratified interactions in the V3 loop of the HIV-1 envelope.

The third variable loop (V3) of the human immunodeficiency virus type 1 (HIV-1) envelope is a principal determinant of antibody neutralization and progression to AIDS. Although it is undoubtedly an important target for vaccine research, extensive genetic variation in V3 remains an obstacle to the de...

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Bibliographic Details
Main Authors: Art F Y Poon, Fraser I Lewis, Sergei L Kosakovsky Pond, Simon D W Frost
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2007
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Online Access:https://doaj.org/article/12a622b4b6704e47ae2c719be2b986ed
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