Multifunctional Electrospun Nanofibers Based on Biopolymer Blends and Magnetic Tubular Halloysite for Medical Applications

Tubular halloysite (HNT) is a naturally occurring aluminosilicate clay with a unique combination of natural availability, good biocompatibility, high mechanical strength, and functionality. This study explored the effects of magnetically responsive halloysite (MHNT) on the structure, morphology, che...

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Autores principales:	Viera Khunová, David Pavliňák, Ivo Šafařík, Martin Škrátek, František Ondreáš
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	magnetic halloysite nanotubes nanofibers biopolymer polycaprolactone Organic chemistry QD241-441
Acceso en línea:	https://doaj.org/article/12a7bbb077514d2bbf2c4d23408a77e1
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spelling	oai:doaj.org-article:12a7bbb077514d2bbf2c4d23408a77e12021-11-25T18:47:48ZMultifunctional Electrospun Nanofibers Based on Biopolymer Blends and Magnetic Tubular Halloysite for Medical Applications10.3390/polym132238702073-4360https://doaj.org/article/12a7bbb077514d2bbf2c4d23408a77e12021-11-01T00:00:00Zhttps://www.mdpi.com/2073-4360/13/22/3870https://doaj.org/toc/2073-4360Tubular halloysite (HNT) is a naturally occurring aluminosilicate clay with a unique combination of natural availability, good biocompatibility, high mechanical strength, and functionality. This study explored the effects of magnetically responsive halloysite (MHNT) on the structure, morphology, chemical composition, and magnetic and mechanical properties of electrospun nanofibers based on polycaprolactone (PCL) and gelatine (Gel) blends. MHNT was prepared via a simple modification of HNT with a perchloric-acid-stabilized magnetic fluid–methanol mixture. PCL/Gel nanofibers containing 6, 9, and 12 wt.% HNT and MHNT were prepared via an electrospinning process, respecting the essential rules for medical applications. The structure and properties of the prepared nanofibers were studied using infrared spectroscopy (ATR-FTIR) and electron microscopy (SEM, STEM) along with energy-dispersive X-ray spectroscopy (EDX), magnetometry, and mechanical analysis. It was found that the incorporation of the studied concentrations of MHNT into PCL/Gel nanofibers led to soft magnetic biocompatible materials with a saturation magnetization of 0.67 emu/g and coercivity of 15 Oe for nanofibers with 12 wt.% MHNT. Moreover, by applying both HNT and MHNT, an improvement of the nanofibers structure was observed, together with strong reinforcing effects. The greatest improvement was observed for nanofibers containing 9 wt.% MHNT when increases in tensile strength reached more than two-fold and the elongation at break reached a five-fold improvement.Viera KhunováDavid PavliňákIvo ŠafaříkMartin ŠkrátekFrantišek OndreášMDPI AGarticlemagnetichalloysitenanotubesnanofibersbiopolymerpolycaprolactoneOrganic chemistryQD241-441ENPolymers, Vol 13, Iss 3870, p 3870 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	magnetic halloysite nanotubes nanofibers biopolymer polycaprolactone Organic chemistry QD241-441
spellingShingle	magnetic halloysite nanotubes nanofibers biopolymer polycaprolactone Organic chemistry QD241-441 Viera Khunová David Pavliňák Ivo Šafařík Martin Škrátek František Ondreáš Multifunctional Electrospun Nanofibers Based on Biopolymer Blends and Magnetic Tubular Halloysite for Medical Applications
description	Tubular halloysite (HNT) is a naturally occurring aluminosilicate clay with a unique combination of natural availability, good biocompatibility, high mechanical strength, and functionality. This study explored the effects of magnetically responsive halloysite (MHNT) on the structure, morphology, chemical composition, and magnetic and mechanical properties of electrospun nanofibers based on polycaprolactone (PCL) and gelatine (Gel) blends. MHNT was prepared via a simple modification of HNT with a perchloric-acid-stabilized magnetic fluid–methanol mixture. PCL/Gel nanofibers containing 6, 9, and 12 wt.% HNT and MHNT were prepared via an electrospinning process, respecting the essential rules for medical applications. The structure and properties of the prepared nanofibers were studied using infrared spectroscopy (ATR-FTIR) and electron microscopy (SEM, STEM) along with energy-dispersive X-ray spectroscopy (EDX), magnetometry, and mechanical analysis. It was found that the incorporation of the studied concentrations of MHNT into PCL/Gel nanofibers led to soft magnetic biocompatible materials with a saturation magnetization of 0.67 emu/g and coercivity of 15 Oe for nanofibers with 12 wt.% MHNT. Moreover, by applying both HNT and MHNT, an improvement of the nanofibers structure was observed, together with strong reinforcing effects. The greatest improvement was observed for nanofibers containing 9 wt.% MHNT when increases in tensile strength reached more than two-fold and the elongation at break reached a five-fold improvement.
format	article
author	Viera Khunová David Pavliňák Ivo Šafařík Martin Škrátek František Ondreáš
author_facet	Viera Khunová David Pavliňák Ivo Šafařík Martin Škrátek František Ondreáš
author_sort	Viera Khunová
title	Multifunctional Electrospun Nanofibers Based on Biopolymer Blends and Magnetic Tubular Halloysite for Medical Applications
title_short	Multifunctional Electrospun Nanofibers Based on Biopolymer Blends and Magnetic Tubular Halloysite for Medical Applications
title_full	Multifunctional Electrospun Nanofibers Based on Biopolymer Blends and Magnetic Tubular Halloysite for Medical Applications
title_fullStr	Multifunctional Electrospun Nanofibers Based on Biopolymer Blends and Magnetic Tubular Halloysite for Medical Applications
title_full_unstemmed	Multifunctional Electrospun Nanofibers Based on Biopolymer Blends and Magnetic Tubular Halloysite for Medical Applications
title_sort	multifunctional electrospun nanofibers based on biopolymer blends and magnetic tubular halloysite for medical applications
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/12a7bbb077514d2bbf2c4d23408a77e1
work_keys_str_mv	AT vierakhunova multifunctionalelectrospunnanofibersbasedonbiopolymerblendsandmagnetictubularhalloysiteformedicalapplications AT davidpavlinak multifunctionalelectrospunnanofibersbasedonbiopolymerblendsandmagnetictubularhalloysiteformedicalapplications AT ivosafarik multifunctionalelectrospunnanofibersbasedonbiopolymerblendsandmagnetictubularhalloysiteformedicalapplications AT martinskratek multifunctionalelectrospunnanofibersbasedonbiopolymerblendsandmagnetictubularhalloysiteformedicalapplications AT frantisekondreas multifunctionalelectrospunnanofibersbasedonbiopolymerblendsandmagnetictubularhalloysiteformedicalapplications
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Multifunctional Electrospun Nanofibers Based on Biopolymer Blends and Magnetic Tubular Halloysite for Medical Applications

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