Visible light-induced direct α C–H functionalization of alcohols

Alcohols are very useful building blocks in organic synthesis, however C–H functionaliztion in presence of free –OH groups is highly challenging. Here, the authors report a selective visible light-promoted α-functionalization of free alcohols with heteroarenes mediated by Selectofluor.

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Autores principales: Linbin Niu, Jiamei Liu, Xing-An Liang, Shengchun Wang, Aiwen Lei
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/12a8b47afd99453b9fd4578a86b1235e
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spelling oai:doaj.org-article:12a8b47afd99453b9fd4578a86b1235e2021-12-02T15:35:48ZVisible light-induced direct α C–H functionalization of alcohols10.1038/s41467-019-08413-92041-1723https://doaj.org/article/12a8b47afd99453b9fd4578a86b1235e2019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08413-9https://doaj.org/toc/2041-1723Alcohols are very useful building blocks in organic synthesis, however C–H functionaliztion in presence of free –OH groups is highly challenging. Here, the authors report a selective visible light-promoted α-functionalization of free alcohols with heteroarenes mediated by Selectofluor.Linbin NiuJiamei LiuXing-An LiangShengchun WangAiwen LeiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Linbin Niu
Jiamei Liu
Xing-An Liang
Shengchun Wang
Aiwen Lei
Visible light-induced direct α C–H functionalization of alcohols
description Alcohols are very useful building blocks in organic synthesis, however C–H functionaliztion in presence of free –OH groups is highly challenging. Here, the authors report a selective visible light-promoted α-functionalization of free alcohols with heteroarenes mediated by Selectofluor.
format article
author Linbin Niu
Jiamei Liu
Xing-An Liang
Shengchun Wang
Aiwen Lei
author_facet Linbin Niu
Jiamei Liu
Xing-An Liang
Shengchun Wang
Aiwen Lei
author_sort Linbin Niu
title Visible light-induced direct α C–H functionalization of alcohols
title_short Visible light-induced direct α C–H functionalization of alcohols
title_full Visible light-induced direct α C–H functionalization of alcohols
title_fullStr Visible light-induced direct α C–H functionalization of alcohols
title_full_unstemmed Visible light-induced direct α C–H functionalization of alcohols
title_sort visible light-induced direct α c–h functionalization of alcohols
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/12a8b47afd99453b9fd4578a86b1235e
work_keys_str_mv AT linbinniu visiblelightinduceddirectachfunctionalizationofalcohols
AT jiameiliu visiblelightinduceddirectachfunctionalizationofalcohols
AT xinganliang visiblelightinduceddirectachfunctionalizationofalcohols
AT shengchunwang visiblelightinduceddirectachfunctionalizationofalcohols
AT aiwenlei visiblelightinduceddirectachfunctionalizationofalcohols
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