α-Synuclein oligomers induced by docosahexaenoic acid affect membrane integrity.

A key feature of Parkinson disease is the aggregation of α-synuclein and its intracellular deposition in fibrillar form. Increasing evidence suggests that the pathogenicity of α-synuclein is correlated with the activity of oligomers formed in the early stages of its aggregation process. Oligomers to...

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Auteurs principaux: Chiara Fecchio, Giorgia De Franceschi, Annalisa Relini, Elisa Greggio, Mauro Dalla Serra, Luigi Bubacco, Patrizia Polverino de Laureto
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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R
Q
Accès en ligne:https://doaj.org/article/12c2a16eb78f43d49ad4ac85fff00719
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