Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles

Tumour samples are heterogeneous and are comprised of multiple cell types in addition to cancer cells. Here, the authors devised a method to estimate the relative levels of haematopoietic cells in breast cancer samples and demonstrate that this correlates with prognosis.

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Detalles Bibliográficos
Autores principales: Frederick S. Varn, Erik H. Andrews, David W. Mullins, Chao Cheng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/12d103b3d080434da061c3d03435a48e
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Descripción
Sumario:Tumour samples are heterogeneous and are comprised of multiple cell types in addition to cancer cells. Here, the authors devised a method to estimate the relative levels of haematopoietic cells in breast cancer samples and demonstrate that this correlates with prognosis.