Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles

Tumour samples are heterogeneous and are comprised of multiple cell types in addition to cancer cells. Here, the authors devised a method to estimate the relative levels of haematopoietic cells in breast cancer samples and demonstrate that this correlates with prognosis.

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Autores principales: Frederick S. Varn, Erik H. Andrews, David W. Mullins, Chao Cheng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/12d103b3d080434da061c3d03435a48e
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spelling oai:doaj.org-article:12d103b3d080434da061c3d03435a48e2021-12-02T17:32:50ZIntegrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles10.1038/ncomms102482041-1723https://doaj.org/article/12d103b3d080434da061c3d03435a48e2016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10248https://doaj.org/toc/2041-1723Tumour samples are heterogeneous and are comprised of multiple cell types in addition to cancer cells. Here, the authors devised a method to estimate the relative levels of haematopoietic cells in breast cancer samples and demonstrate that this correlates with prognosis.Frederick S. VarnErik H. AndrewsDavid W. MullinsChao ChengNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Frederick S. Varn
Erik H. Andrews
David W. Mullins
Chao Cheng
Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles
description Tumour samples are heterogeneous and are comprised of multiple cell types in addition to cancer cells. Here, the authors devised a method to estimate the relative levels of haematopoietic cells in breast cancer samples and demonstrate that this correlates with prognosis.
format article
author Frederick S. Varn
Erik H. Andrews
David W. Mullins
Chao Cheng
author_facet Frederick S. Varn
Erik H. Andrews
David W. Mullins
Chao Cheng
author_sort Frederick S. Varn
title Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles
title_short Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles
title_full Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles
title_fullStr Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles
title_full_unstemmed Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles
title_sort integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/12d103b3d080434da061c3d03435a48e
work_keys_str_mv AT fredericksvarn integrativeanalysisofbreastcancerrevealsprognostichaematopoieticactivityandpatientspecificimmuneresponseprofiles
AT erikhandrews integrativeanalysisofbreastcancerrevealsprognostichaematopoieticactivityandpatientspecificimmuneresponseprofiles
AT davidwmullins integrativeanalysisofbreastcancerrevealsprognostichaematopoieticactivityandpatientspecificimmuneresponseprofiles
AT chaocheng integrativeanalysisofbreastcancerrevealsprognostichaematopoieticactivityandpatientspecificimmuneresponseprofiles
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