Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles

Tumour samples are heterogeneous and are comprised of multiple cell types in addition to cancer cells. Here, the authors devised a method to estimate the relative levels of haematopoietic cells in breast cancer samples and demonstrate that this correlates with prognosis.

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Bibliographic Details
Main Authors:	Frederick S. Varn, Erik H. Andrews, David W. Mullins, Chao Cheng
Format:	article
Language:	EN
Published:	Nature Portfolio 2016
Subjects:	Science Q
Online Access:	https://doaj.org/article/12d103b3d080434da061c3d03435a48e
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spelling	oai:doaj.org-article:12d103b3d080434da061c3d03435a48e2021-12-02T17:32:50ZIntegrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles10.1038/ncomms102482041-1723https://doaj.org/article/12d103b3d080434da061c3d03435a48e2016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10248https://doaj.org/toc/2041-1723Tumour samples are heterogeneous and are comprised of multiple cell types in addition to cancer cells. Here, the authors devised a method to estimate the relative levels of haematopoietic cells in breast cancer samples and demonstrate that this correlates with prognosis.Frederick S. VarnErik H. AndrewsDavid W. MullinsChao ChengNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Frederick S. Varn Erik H. Andrews David W. Mullins Chao Cheng Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles
description	Tumour samples are heterogeneous and are comprised of multiple cell types in addition to cancer cells. Here, the authors devised a method to estimate the relative levels of haematopoietic cells in breast cancer samples and demonstrate that this correlates with prognosis.
format	article
author	Frederick S. Varn Erik H. Andrews David W. Mullins Chao Cheng
author_facet	Frederick S. Varn Erik H. Andrews David W. Mullins Chao Cheng
author_sort	Frederick S. Varn
title	Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles
title_short	Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles
title_full	Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles
title_fullStr	Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles
title_full_unstemmed	Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles
title_sort	integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/12d103b3d080434da061c3d03435a48e
work_keys_str_mv	AT fredericksvarn integrativeanalysisofbreastcancerrevealsprognostichaematopoieticactivityandpatientspecificimmuneresponseprofiles AT erikhandrews integrativeanalysisofbreastcancerrevealsprognostichaematopoieticactivityandpatientspecificimmuneresponseprofiles AT davidwmullins integrativeanalysisofbreastcancerrevealsprognostichaematopoieticactivityandpatientspecificimmuneresponseprofiles AT chaocheng integrativeanalysisofbreastcancerrevealsprognostichaematopoieticactivityandpatientspecificimmuneresponseprofiles
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Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles

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