The predictive role of monocyte-lymphocyte ratio and plateletlymphocyte ratio in postmenopausal osteoporosis

Objective. To investigate the relationship between neutrophil to lymphocyte ratio (NEU/LY), monocyte to lymphocyte ratio (MO/LY), platelet to lymphocyte ratio (PLT/LY), mean platelet volume to lymphocyte ratio (MPV/LY), mean platelet volume to platelet ratio (MPV/PLT), plateletcrit to platelet ratio...

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Autor principal:	Ibrahim Kale
Formato:	article
Lenguaje:	EN
Publicado:	Digital ProScholar Media 2021
Materias:	monocyte-lymphocyte ratio platelet-lymphocyte ratio postmenopausal osteoporosis Medicine R
Acceso en línea:	https://doaj.org/article/12d10c7686b74c1d81432656b6bb47f4
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spelling	oai:doaj.org-article:12d10c7686b74c1d81432656b6bb47f42021-11-23T17:13:07ZThe predictive role of monocyte-lymphocyte ratio and plateletlymphocyte ratio in postmenopausal osteoporosis10.25083/2559.5555/6.2.92559-5555https://doaj.org/article/12d10c7686b74c1d81432656b6bb47f42021-11-01T00:00:00Zhttps://www.e-repository.org/jcis/6/2/9.pdfhttps://doaj.org/toc/2559-5555Objective. To investigate the relationship between neutrophil to lymphocyte ratio (NEU/LY), monocyte to lymphocyte ratio (MO/LY), platelet to lymphocyte ratio (PLT/LY), mean platelet volume to lymphocyte ratio (MPV/LY), mean platelet volume to platelet ratio (MPV/PLT), plateletcrit to platelet ratio (PCT/PLT) and postmenopausal osteoporosis. Materials and Methods. The data of the patients who were admitted to Ümraniye Training and Research Hospital between January 2017 and July 2020 and had both bone mineral densitometry and hemogram tests on the same day were retrospectively scanned. A number of 177 patients who had been in natural menopause for at least one year and did not have any chronic disease nor used any medication were first divided into 3 groups: a number of 48 patients with osteoporosis, 103 with osteopenia and 26 patients included in the control group. Later on, 177 patients were divided into two groups: 151 patients with low bone mineral density and 26 patients were included in the control group. Results. There was no difference between the three groups in terms of NEU/LY, MPV/LY, MPV/PLT and PCT/PLT. The MO/LY ratio and PLT/LY ratio were statistically significantly higher in the osteoporosis group (p = 0.002, p <0.001, respectively). The MO/LY ratio was significantly higher in the group with low bone mineral density compared to the control group (p = 0.011), while there was no statistical difference between the two groups in terms of PLT/LY ratio (p = 0.281). Conclusions. This study shows that MO/LY and PLT/LY are quite simple and cheap markers that can be used in the diagnosis of postmenopausal osteoporosis and MO/LY in the diagnosis of postmenopausal low bone mineral density.Ibrahim KaleDigital ProScholar Mediaarticlemonocyte-lymphocyte ratioplatelet-lymphocyte ratiopostmenopausal osteoporosisMedicineRENJournal of Clinical and Investigative Surgery, Vol 6, Iss 2, Pp 141-147 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	monocyte-lymphocyte ratio platelet-lymphocyte ratio postmenopausal osteoporosis Medicine R
spellingShingle	monocyte-lymphocyte ratio platelet-lymphocyte ratio postmenopausal osteoporosis Medicine R Ibrahim Kale The predictive role of monocyte-lymphocyte ratio and plateletlymphocyte ratio in postmenopausal osteoporosis
description	Objective. To investigate the relationship between neutrophil to lymphocyte ratio (NEU/LY), monocyte to lymphocyte ratio (MO/LY), platelet to lymphocyte ratio (PLT/LY), mean platelet volume to lymphocyte ratio (MPV/LY), mean platelet volume to platelet ratio (MPV/PLT), plateletcrit to platelet ratio (PCT/PLT) and postmenopausal osteoporosis. Materials and Methods. The data of the patients who were admitted to Ümraniye Training and Research Hospital between January 2017 and July 2020 and had both bone mineral densitometry and hemogram tests on the same day were retrospectively scanned. A number of 177 patients who had been in natural menopause for at least one year and did not have any chronic disease nor used any medication were first divided into 3 groups: a number of 48 patients with osteoporosis, 103 with osteopenia and 26 patients included in the control group. Later on, 177 patients were divided into two groups: 151 patients with low bone mineral density and 26 patients were included in the control group. Results. There was no difference between the three groups in terms of NEU/LY, MPV/LY, MPV/PLT and PCT/PLT. The MO/LY ratio and PLT/LY ratio were statistically significantly higher in the osteoporosis group (p = 0.002, p <0.001, respectively). The MO/LY ratio was significantly higher in the group with low bone mineral density compared to the control group (p = 0.011), while there was no statistical difference between the two groups in terms of PLT/LY ratio (p = 0.281). Conclusions. This study shows that MO/LY and PLT/LY are quite simple and cheap markers that can be used in the diagnosis of postmenopausal osteoporosis and MO/LY in the diagnosis of postmenopausal low bone mineral density.
format	article
author	Ibrahim Kale
author_facet	Ibrahim Kale
author_sort	Ibrahim Kale
title	The predictive role of monocyte-lymphocyte ratio and plateletlymphocyte ratio in postmenopausal osteoporosis
title_short	The predictive role of monocyte-lymphocyte ratio and plateletlymphocyte ratio in postmenopausal osteoporosis
title_full	The predictive role of monocyte-lymphocyte ratio and plateletlymphocyte ratio in postmenopausal osteoporosis
title_fullStr	The predictive role of monocyte-lymphocyte ratio and plateletlymphocyte ratio in postmenopausal osteoporosis
title_full_unstemmed	The predictive role of monocyte-lymphocyte ratio and plateletlymphocyte ratio in postmenopausal osteoporosis
title_sort	predictive role of monocyte-lymphocyte ratio and plateletlymphocyte ratio in postmenopausal osteoporosis
publisher	Digital ProScholar Media
publishDate	2021
url	https://doaj.org/article/12d10c7686b74c1d81432656b6bb47f4
work_keys_str_mv	AT ibrahimkale thepredictiveroleofmonocytelymphocyteratioandplateletlymphocyteratioinpostmenopausalosteoporosis AT ibrahimkale predictiveroleofmonocytelymphocyteratioandplateletlymphocyteratioinpostmenopausalosteoporosis
_version_	1718416195659497472

The predictive role of monocyte-lymphocyte ratio and plateletlymphocyte ratio in postmenopausal osteoporosis

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