Dscam1 establishes the columnar units through lineage-dependent repulsion between sister neurons in the fly brain

Columns are the functional and morphological unit of the brain, but how neurons assemble into this structure was unclear. Here, the authors show that Dscam gene rewires neurons that derive from the same stem cell to establish columns through the process of lineage-dependent repulsion.

Guardado en:

Detalles Bibliográficos
Autores principales:	Chuyan Liu, Olena Trush, Xujun Han, Miaoxing Wang, Rie Takayama, Tetsuo Yasugi, Takashi Hayashi, Makoto Sato
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/12d5905512974615a1b2887554ece581
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:12d5905512974615a1b2887554ece581
record_format	dspace
spelling	oai:doaj.org-article:12d5905512974615a1b2887554ece5812021-12-02T18:50:45ZDscam1 establishes the columnar units through lineage-dependent repulsion between sister neurons in the fly brain10.1038/s41467-020-17931-w2041-1723https://doaj.org/article/12d5905512974615a1b2887554ece5812020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17931-whttps://doaj.org/toc/2041-1723Columns are the functional and morphological unit of the brain, but how neurons assemble into this structure was unclear. Here, the authors show that Dscam gene rewires neurons that derive from the same stem cell to establish columns through the process of lineage-dependent repulsion.Chuyan LiuOlena TrushXujun HanMiaoxing WangRie TakayamaTetsuo YasugiTakashi HayashiMakoto SatoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chuyan Liu Olena Trush Xujun Han Miaoxing Wang Rie Takayama Tetsuo Yasugi Takashi Hayashi Makoto Sato Dscam1 establishes the columnar units through lineage-dependent repulsion between sister neurons in the fly brain
description	Columns are the functional and morphological unit of the brain, but how neurons assemble into this structure was unclear. Here, the authors show that Dscam gene rewires neurons that derive from the same stem cell to establish columns through the process of lineage-dependent repulsion.
format	article
author	Chuyan Liu Olena Trush Xujun Han Miaoxing Wang Rie Takayama Tetsuo Yasugi Takashi Hayashi Makoto Sato
author_facet	Chuyan Liu Olena Trush Xujun Han Miaoxing Wang Rie Takayama Tetsuo Yasugi Takashi Hayashi Makoto Sato
author_sort	Chuyan Liu
title	Dscam1 establishes the columnar units through lineage-dependent repulsion between sister neurons in the fly brain
title_short	Dscam1 establishes the columnar units through lineage-dependent repulsion between sister neurons in the fly brain
title_full	Dscam1 establishes the columnar units through lineage-dependent repulsion between sister neurons in the fly brain
title_fullStr	Dscam1 establishes the columnar units through lineage-dependent repulsion between sister neurons in the fly brain
title_full_unstemmed	Dscam1 establishes the columnar units through lineage-dependent repulsion between sister neurons in the fly brain
title_sort	dscam1 establishes the columnar units through lineage-dependent repulsion between sister neurons in the fly brain
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/12d5905512974615a1b2887554ece581
work_keys_str_mv	AT chuyanliu dscam1establishesthecolumnarunitsthroughlineagedependentrepulsionbetweensisterneuronsintheflybrain AT olenatrush dscam1establishesthecolumnarunitsthroughlineagedependentrepulsionbetweensisterneuronsintheflybrain AT xujunhan dscam1establishesthecolumnarunitsthroughlineagedependentrepulsionbetweensisterneuronsintheflybrain AT miaoxingwang dscam1establishesthecolumnarunitsthroughlineagedependentrepulsionbetweensisterneuronsintheflybrain AT rietakayama dscam1establishesthecolumnarunitsthroughlineagedependentrepulsionbetweensisterneuronsintheflybrain AT tetsuoyasugi dscam1establishesthecolumnarunitsthroughlineagedependentrepulsionbetweensisterneuronsintheflybrain AT takashihayashi dscam1establishesthecolumnarunitsthroughlineagedependentrepulsionbetweensisterneuronsintheflybrain AT makotosato dscam1establishesthecolumnarunitsthroughlineagedependentrepulsionbetweensisterneuronsintheflybrain
_version_	1718377486925955072

Dscam1 establishes the columnar units through lineage-dependent repulsion between sister neurons in the fly brain

Ejemplares similares