Dscam1 establishes the columnar units through lineage-dependent repulsion between sister neurons in the fly brain

Columns are the functional and morphological unit of the brain, but how neurons assemble into this structure was unclear. Here, the authors show that Dscam gene rewires neurons that derive from the same stem cell to establish columns through the process of lineage-dependent repulsion.

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Auteurs principaux: Chuyan Liu, Olena Trush, Xujun Han, Miaoxing Wang, Rie Takayama, Tetsuo Yasugi, Takashi Hayashi, Makoto Sato
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/12d5905512974615a1b2887554ece581
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