The conserved single-cleavage mechanism of animal DROSHA enzymes

Recently, the human RNase III enzyme DROSHA had been shown to exhibit single cleavage activity. Nguyen et al. report that this molecular mechanism of DROSHA is conserved in worms and flies, suggesting a common feature of animal DROSHAs.

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Detalles Bibliográficos
Autores principales: Thuy Linh Nguyen, Trung Duc Nguyen, Tuan Anh Nguyen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/12d61497ac584c6e9d256db6f834027b
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Sumario:Recently, the human RNase III enzyme DROSHA had been shown to exhibit single cleavage activity. Nguyen et al. report that this molecular mechanism of DROSHA is conserved in worms and flies, suggesting a common feature of animal DROSHAs.