The conserved single-cleavage mechanism of animal DROSHA enzymes

Recently, the human RNase III enzyme DROSHA had been shown to exhibit single cleavage activity. Nguyen et al. report that this molecular mechanism of DROSHA is conserved in worms and flies, suggesting a common feature of animal DROSHAs.

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Auteurs principaux: Thuy Linh Nguyen, Trung Duc Nguyen, Tuan Anh Nguyen
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/12d61497ac584c6e9d256db6f834027b
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Résumé:Recently, the human RNase III enzyme DROSHA had been shown to exhibit single cleavage activity. Nguyen et al. report that this molecular mechanism of DROSHA is conserved in worms and flies, suggesting a common feature of animal DROSHAs.