The conserved single-cleavage mechanism of animal DROSHA enzymes

Recently, the human RNase III enzyme DROSHA had been shown to exhibit single cleavage activity. Nguyen et al. report that this molecular mechanism of DROSHA is conserved in worms and flies, suggesting a common feature of animal DROSHAs.

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Auteurs principaux: Thuy Linh Nguyen, Trung Duc Nguyen, Tuan Anh Nguyen
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/12d61497ac584c6e9d256db6f834027b
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spelling oai:doaj.org-article:12d61497ac584c6e9d256db6f834027b2021-11-28T12:10:21ZThe conserved single-cleavage mechanism of animal DROSHA enzymes10.1038/s42003-021-02860-12399-3642https://doaj.org/article/12d61497ac584c6e9d256db6f834027b2021-11-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02860-1https://doaj.org/toc/2399-3642Recently, the human RNase III enzyme DROSHA had been shown to exhibit single cleavage activity. Nguyen et al. report that this molecular mechanism of DROSHA is conserved in worms and flies, suggesting a common feature of animal DROSHAs.Thuy Linh NguyenTrung Duc NguyenTuan Anh NguyenNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Thuy Linh Nguyen
Trung Duc Nguyen
Tuan Anh Nguyen
The conserved single-cleavage mechanism of animal DROSHA enzymes
description Recently, the human RNase III enzyme DROSHA had been shown to exhibit single cleavage activity. Nguyen et al. report that this molecular mechanism of DROSHA is conserved in worms and flies, suggesting a common feature of animal DROSHAs.
format article
author Thuy Linh Nguyen
Trung Duc Nguyen
Tuan Anh Nguyen
author_facet Thuy Linh Nguyen
Trung Duc Nguyen
Tuan Anh Nguyen
author_sort Thuy Linh Nguyen
title The conserved single-cleavage mechanism of animal DROSHA enzymes
title_short The conserved single-cleavage mechanism of animal DROSHA enzymes
title_full The conserved single-cleavage mechanism of animal DROSHA enzymes
title_fullStr The conserved single-cleavage mechanism of animal DROSHA enzymes
title_full_unstemmed The conserved single-cleavage mechanism of animal DROSHA enzymes
title_sort conserved single-cleavage mechanism of animal drosha enzymes
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/12d61497ac584c6e9d256db6f834027b
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