Towards an arthritis flare-responsive drug delivery system
The treatment of inflammatory arthritis by local delivery of therapeutics is limited by short half-lives of drugs. Here the authors demonstrate a hydrogel platform that titrates drug release to arthritis activity.
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Nature Portfolio
2018
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oai:doaj.org-article:12e29ed0087e4d67868b51dbfbcd8c912021-12-02T14:39:23ZTowards an arthritis flare-responsive drug delivery system10.1038/s41467-018-03691-12041-1723https://doaj.org/article/12e29ed0087e4d67868b51dbfbcd8c912018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03691-1https://doaj.org/toc/2041-1723The treatment of inflammatory arthritis by local delivery of therapeutics is limited by short half-lives of drugs. Here the authors demonstrate a hydrogel platform that titrates drug release to arthritis activity.Nitin JoshiJing YanSeth LevySachin BhagchandaniKai V. SlaughterNicholas E. ShermanJulian AmiraultYufeng WangLogan RiegelXueyin HeTan Shi RuiMichael ValicPraveen K. VemulaOscar R. MirandaOren LevyEllen M. GravalleseAntonios O. AliprantisJoerg ErmannJeffrey M. KarpNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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DOAJ |
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DOAJ |
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EN |
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Science Q |
spellingShingle |
Science Q Nitin Joshi Jing Yan Seth Levy Sachin Bhagchandani Kai V. Slaughter Nicholas E. Sherman Julian Amirault Yufeng Wang Logan Riegel Xueyin He Tan Shi Rui Michael Valic Praveen K. Vemula Oscar R. Miranda Oren Levy Ellen M. Gravallese Antonios O. Aliprantis Joerg Ermann Jeffrey M. Karp Towards an arthritis flare-responsive drug delivery system |
description |
The treatment of inflammatory arthritis by local delivery of therapeutics is limited by short half-lives of drugs. Here the authors demonstrate a hydrogel platform that titrates drug release to arthritis activity. |
format |
article |
author |
Nitin Joshi Jing Yan Seth Levy Sachin Bhagchandani Kai V. Slaughter Nicholas E. Sherman Julian Amirault Yufeng Wang Logan Riegel Xueyin He Tan Shi Rui Michael Valic Praveen K. Vemula Oscar R. Miranda Oren Levy Ellen M. Gravallese Antonios O. Aliprantis Joerg Ermann Jeffrey M. Karp |
author_facet |
Nitin Joshi Jing Yan Seth Levy Sachin Bhagchandani Kai V. Slaughter Nicholas E. Sherman Julian Amirault Yufeng Wang Logan Riegel Xueyin He Tan Shi Rui Michael Valic Praveen K. Vemula Oscar R. Miranda Oren Levy Ellen M. Gravallese Antonios O. Aliprantis Joerg Ermann Jeffrey M. Karp |
author_sort |
Nitin Joshi |
title |
Towards an arthritis flare-responsive drug delivery system |
title_short |
Towards an arthritis flare-responsive drug delivery system |
title_full |
Towards an arthritis flare-responsive drug delivery system |
title_fullStr |
Towards an arthritis flare-responsive drug delivery system |
title_full_unstemmed |
Towards an arthritis flare-responsive drug delivery system |
title_sort |
towards an arthritis flare-responsive drug delivery system |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/12e29ed0087e4d67868b51dbfbcd8c91 |
work_keys_str_mv |
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