Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs

Abstract Easy-to-prepare drug delivery systems, based on smart, silica gels have been synthesized, characterized, and studied as hosts in the controlled release of bisphosphonates. They exhibit variable release rates and final % release, depending on the nature of bisphosphonate (side-chain length,...

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Autores principales:	Konstantinos E. Papathanasiou, Petri Turhanen, Stephan I. Brückner, Eike Brunner, Konstantinos D. Demadis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/12e5a874b648443a9f5ab1b71f010d3c
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spelling	oai:doaj.org-article:12e5a874b648443a9f5ab1b71f010d3c2021-12-02T12:30:25ZSmart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs10.1038/s41598-017-04956-32045-2322https://doaj.org/article/12e5a874b648443a9f5ab1b71f010d3c2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-04956-3https://doaj.org/toc/2045-2322Abstract Easy-to-prepare drug delivery systems, based on smart, silica gels have been synthesized, characterized, and studied as hosts in the controlled release of bisphosphonates. They exhibit variable release rates and final % release, depending on the nature of bisphosphonate (side-chain length, hydro-philicity/-phobicity, water-solubility), cations present, pH and temperature. These gels are robust, injectable, re-loadable and re-usable.Konstantinos E. PapathanasiouPetri TurhanenStephan I. BrücknerEike BrunnerKonstantinos D. DemadisNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Konstantinos E. Papathanasiou Petri Turhanen Stephan I. Brückner Eike Brunner Konstantinos D. Demadis Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs
description	Abstract Easy-to-prepare drug delivery systems, based on smart, silica gels have been synthesized, characterized, and studied as hosts in the controlled release of bisphosphonates. They exhibit variable release rates and final % release, depending on the nature of bisphosphonate (side-chain length, hydro-philicity/-phobicity, water-solubility), cations present, pH and temperature. These gels are robust, injectable, re-loadable and re-usable.
format	article
author	Konstantinos E. Papathanasiou Petri Turhanen Stephan I. Brückner Eike Brunner Konstantinos D. Demadis
author_facet	Konstantinos E. Papathanasiou Petri Turhanen Stephan I. Brückner Eike Brunner Konstantinos D. Demadis
author_sort	Konstantinos E. Papathanasiou
title	Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs
title_short	Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs
title_full	Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs
title_fullStr	Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs
title_full_unstemmed	Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs
title_sort	smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/12e5a874b648443a9f5ab1b71f010d3c
work_keys_str_mv	AT konstantinosepapathanasiou smartprogrammableandresponsiveinjectablehydrogelsforcontrolledreleaseofcargoosteoporosisdrugs AT petriturhanen smartprogrammableandresponsiveinjectablehydrogelsforcontrolledreleaseofcargoosteoporosisdrugs AT stephanibruckner smartprogrammableandresponsiveinjectablehydrogelsforcontrolledreleaseofcargoosteoporosisdrugs AT eikebrunner smartprogrammableandresponsiveinjectablehydrogelsforcontrolledreleaseofcargoosteoporosisdrugs AT konstantinosddemadis smartprogrammableandresponsiveinjectablehydrogelsforcontrolledreleaseofcargoosteoporosisdrugs
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Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs

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