Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA

Memory T cells are essential for combating recurring infection by promoting prompt and effective immune responses. Here the authors show, via system biology approaches, that human CD4 memory T cells contains a CD45RA-rexpressing pool that can be further subsetted by the expression of GPR56 for disti...

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Autores principales:	Yuan Tian, Mariana Babor, Jerome Lane, Veronique Schulten, Veena S. Patil, Grégory Seumois, Sandy L. Rosales, Zheng Fu, Gaelle Picarda, Julie Burel, Jose Zapardiel-Gonzalo, Rashika N. Tennekoon, Aruna D. De Silva, Sunil Premawansa, Gayani Premawansa, Ananda Wijewickrama, Jason A. Greenbaum, Pandurangan Vijayanand, Daniela Weiskopf, Alessandro Sette, Bjoern Peters
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1300a213373847c1bd139605b64d5245
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spelling	oai:doaj.org-article:1300a213373847c1bd139605b64d52452021-12-02T14:40:47ZUnique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA10.1038/s41467-017-01728-52041-1723https://doaj.org/article/1300a213373847c1bd139605b64d52452017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01728-5https://doaj.org/toc/2041-1723Memory T cells are essential for combating recurring infection by promoting prompt and effective immune responses. Here the authors show, via system biology approaches, that human CD4 memory T cells contains a CD45RA-rexpressing pool that can be further subsetted by the expression of GPR56 for distinct functionalities.Yuan TianMariana BaborJerome LaneVeronique SchultenVeena S. PatilGrégory SeumoisSandy L. RosalesZheng FuGaelle PicardaJulie BurelJose Zapardiel-GonzaloRashika N. TennekoonAruna D. De SilvaSunil PremawansaGayani PremawansaAnanda WijewickramaJason A. GreenbaumPandurangan VijayanandDaniela WeiskopfAlessandro SetteBjoern PetersNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuan Tian Mariana Babor Jerome Lane Veronique Schulten Veena S. Patil Grégory Seumois Sandy L. Rosales Zheng Fu Gaelle Picarda Julie Burel Jose Zapardiel-Gonzalo Rashika N. Tennekoon Aruna D. De Silva Sunil Premawansa Gayani Premawansa Ananda Wijewickrama Jason A. Greenbaum Pandurangan Vijayanand Daniela Weiskopf Alessandro Sette Bjoern Peters Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA
description	Memory T cells are essential for combating recurring infection by promoting prompt and effective immune responses. Here the authors show, via system biology approaches, that human CD4 memory T cells contains a CD45RA-rexpressing pool that can be further subsetted by the expression of GPR56 for distinct functionalities.
format	article
author	Yuan Tian Mariana Babor Jerome Lane Veronique Schulten Veena S. Patil Grégory Seumois Sandy L. Rosales Zheng Fu Gaelle Picarda Julie Burel Jose Zapardiel-Gonzalo Rashika N. Tennekoon Aruna D. De Silva Sunil Premawansa Gayani Premawansa Ananda Wijewickrama Jason A. Greenbaum Pandurangan Vijayanand Daniela Weiskopf Alessandro Sette Bjoern Peters
author_facet	Yuan Tian Mariana Babor Jerome Lane Veronique Schulten Veena S. Patil Grégory Seumois Sandy L. Rosales Zheng Fu Gaelle Picarda Julie Burel Jose Zapardiel-Gonzalo Rashika N. Tennekoon Aruna D. De Silva Sunil Premawansa Gayani Premawansa Ananda Wijewickrama Jason A. Greenbaum Pandurangan Vijayanand Daniela Weiskopf Alessandro Sette Bjoern Peters
author_sort	Yuan Tian
title	Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA
title_short	Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA
title_full	Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA
title_fullStr	Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA
title_full_unstemmed	Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA
title_sort	unique phenotypes and clonal expansions of human cd4 effector memory t cells re-expressing cd45ra
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/1300a213373847c1bd139605b64d5245
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Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA

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