Exploring DNA quality of single cells for genome analysis with simultaneous whole-genome amplification

Abstract Single cell genome analysis methods are powerful tools to define features of single cells and to identify differences between them. Since the DNA amount of a single cell is very limited, cellular DNA usually needs to be amplified by whole-genome amplification before being subjected to furth...

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Autores principales: Christiane Bäumer, Evelyn Fisch, Holger Wedler, Frank Reinecke, Christian Korfhage
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/131231fd4bb247beb4186d5286642f07
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