Identification of efficient prokaryotic cell-penetrating peptides with applications in bacterial biotechnology

Lee et al. construct a cell-penetrating peptides (CPP) library and identify CPPs that can penetrate bacterial cells with minimum or no impact on cell viability. For the identified top CPP candidates, their abilities to deliver macromolecules such as I-SceI and Cre recombinase proteins to bacteria ar...

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Autores principales:	Hyang-Mi Lee, Jun Ren, Kha Mong Tran, Byeong-Min Jeon, Won-Ung Park, Hyunjoo Kim, Kyung Eun Lee, Yuna Oh, Myungback Choi, Dae-Sung Kim, Dokyun Na
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/1314e57b090f4bf9a37650f6a651bd3e
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spelling	oai:doaj.org-article:1314e57b090f4bf9a37650f6a651bd3e2021-12-02T10:54:14ZIdentification of efficient prokaryotic cell-penetrating peptides with applications in bacterial biotechnology10.1038/s42003-021-01726-w2399-3642https://doaj.org/article/1314e57b090f4bf9a37650f6a651bd3e2021-02-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01726-whttps://doaj.org/toc/2399-3642Lee et al. construct a cell-penetrating peptides (CPP) library and identify CPPs that can penetrate bacterial cells with minimum or no impact on cell viability. For the identified top CPP candidates, their abilities to deliver macromolecules such as I-SceI and Cre recombinase proteins to bacteria are evaluated as proof-of-concept studies for potential applications.Hyang-Mi LeeJun RenKha Mong TranByeong-Min JeonWon-Ung ParkHyunjoo KimKyung Eun LeeYuna OhMyungback ChoiDae-Sung KimDokyun NaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Hyang-Mi Lee Jun Ren Kha Mong Tran Byeong-Min Jeon Won-Ung Park Hyunjoo Kim Kyung Eun Lee Yuna Oh Myungback Choi Dae-Sung Kim Dokyun Na Identification of efficient prokaryotic cell-penetrating peptides with applications in bacterial biotechnology
description	Lee et al. construct a cell-penetrating peptides (CPP) library and identify CPPs that can penetrate bacterial cells with minimum or no impact on cell viability. For the identified top CPP candidates, their abilities to deliver macromolecules such as I-SceI and Cre recombinase proteins to bacteria are evaluated as proof-of-concept studies for potential applications.
format	article
author	Hyang-Mi Lee Jun Ren Kha Mong Tran Byeong-Min Jeon Won-Ung Park Hyunjoo Kim Kyung Eun Lee Yuna Oh Myungback Choi Dae-Sung Kim Dokyun Na
author_facet	Hyang-Mi Lee Jun Ren Kha Mong Tran Byeong-Min Jeon Won-Ung Park Hyunjoo Kim Kyung Eun Lee Yuna Oh Myungback Choi Dae-Sung Kim Dokyun Na
author_sort	Hyang-Mi Lee
title	Identification of efficient prokaryotic cell-penetrating peptides with applications in bacterial biotechnology
title_short	Identification of efficient prokaryotic cell-penetrating peptides with applications in bacterial biotechnology
title_full	Identification of efficient prokaryotic cell-penetrating peptides with applications in bacterial biotechnology
title_fullStr	Identification of efficient prokaryotic cell-penetrating peptides with applications in bacterial biotechnology
title_full_unstemmed	Identification of efficient prokaryotic cell-penetrating peptides with applications in bacterial biotechnology
title_sort	identification of efficient prokaryotic cell-penetrating peptides with applications in bacterial biotechnology
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1314e57b090f4bf9a37650f6a651bd3e
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Identification of efficient prokaryotic cell-penetrating peptides with applications in bacterial biotechnology

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