HIRA stabilizes skeletal muscle lineage identity

The epigenetic mechanisms coordinating the maintenance of adult cellular lineages remain poorly understood. Here the authors demonstrate that HIRA, a H3.3 histone chaperone, establishes the chromatin landscape required for skeletal muscle cell identity.

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Autores principales:	Joana Esteves de Lima, Reem Bou Akar, Léo Machado, Yuefeng Li, Bernadette Drayton-Libotte, F. Jeffrey Dilworth, Frédéric Relaix
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/131bbfcf00ff49249c28bd0b0b877a5f
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id	oai:doaj.org-article:131bbfcf00ff49249c28bd0b0b877a5f
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spelling	oai:doaj.org-article:131bbfcf00ff49249c28bd0b0b877a5f2021-12-02T18:06:24ZHIRA stabilizes skeletal muscle lineage identity10.1038/s41467-021-23775-92041-1723https://doaj.org/article/131bbfcf00ff49249c28bd0b0b877a5f2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23775-9https://doaj.org/toc/2041-1723The epigenetic mechanisms coordinating the maintenance of adult cellular lineages remain poorly understood. Here the authors demonstrate that HIRA, a H3.3 histone chaperone, establishes the chromatin landscape required for skeletal muscle cell identity.Joana Esteves de LimaReem Bou AkarLéo MachadoYuefeng LiBernadette Drayton-LibotteF. Jeffrey DilworthFrédéric RelaixNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Joana Esteves de Lima Reem Bou Akar Léo Machado Yuefeng Li Bernadette Drayton-Libotte F. Jeffrey Dilworth Frédéric Relaix HIRA stabilizes skeletal muscle lineage identity
description	The epigenetic mechanisms coordinating the maintenance of adult cellular lineages remain poorly understood. Here the authors demonstrate that HIRA, a H3.3 histone chaperone, establishes the chromatin landscape required for skeletal muscle cell identity.
format	article
author	Joana Esteves de Lima Reem Bou Akar Léo Machado Yuefeng Li Bernadette Drayton-Libotte F. Jeffrey Dilworth Frédéric Relaix
author_facet	Joana Esteves de Lima Reem Bou Akar Léo Machado Yuefeng Li Bernadette Drayton-Libotte F. Jeffrey Dilworth Frédéric Relaix
author_sort	Joana Esteves de Lima
title	HIRA stabilizes skeletal muscle lineage identity
title_short	HIRA stabilizes skeletal muscle lineage identity
title_full	HIRA stabilizes skeletal muscle lineage identity
title_fullStr	HIRA stabilizes skeletal muscle lineage identity
title_full_unstemmed	HIRA stabilizes skeletal muscle lineage identity
title_sort	hira stabilizes skeletal muscle lineage identity
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/131bbfcf00ff49249c28bd0b0b877a5f
work_keys_str_mv	AT joanaestevesdelima hirastabilizesskeletalmusclelineageidentity AT reembouakar hirastabilizesskeletalmusclelineageidentity AT leomachado hirastabilizesskeletalmusclelineageidentity AT yuefengli hirastabilizesskeletalmusclelineageidentity AT bernadettedraytonlibotte hirastabilizesskeletalmusclelineageidentity AT fjeffreydilworth hirastabilizesskeletalmusclelineageidentity AT fredericrelaix hirastabilizesskeletalmusclelineageidentity
_version_	1718378613764521984

HIRA stabilizes skeletal muscle lineage identity

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