Anterior chamber angle in aniridia with and without glaucoma

Asima Bajwa,1 Eitan Burstein,1 Robert M Grainger,1,2 Peter A Netland11Department of Ophthalmology, University of Virginia School of Medicine, Charlottesville, VA, USA; 2Department of Biology, University of Virginia, Charlottesville, VA, USAPurpose: We performed a retrospective, comparative study to...

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Autores principales:	Bajwa A, Burstein E, Grainger RM, Netland PA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	aniridia glaucoma anterior segment optical coherence tomography (OCT) gonioscopy Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/13287a9ed76b485eb52603c4da25f203
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spelling	oai:doaj.org-article:13287a9ed76b485eb52603c4da25f2032021-12-02T09:30:15ZAnterior chamber angle in aniridia with and without glaucoma1177-5483https://doaj.org/article/13287a9ed76b485eb52603c4da25f2032019-08-01T00:00:00Zhttps://www.dovepress.com/anterior-chamber-angle-in-aniridia-with-and-without-glaucoma-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Asima Bajwa,1 Eitan Burstein,1 Robert M Grainger,1,2 Peter A Netland11Department of Ophthalmology, University of Virginia School of Medicine, Charlottesville, VA, USA; 2Department of Biology, University of Virginia, Charlottesville, VA, USAPurpose: We performed a retrospective, comparative study to determine if patients with aniridia and glaucoma had open angles on high-resolution anterior segment optical coherence tomography (OCT) and clinical gonioscopy.Patients and methods: Forty-three patients (86 eyes) with aniridia had recorded anterior segment OCTs, gonioscopy, or both. Of these patients, 27 (54 eyes) were diagnosed with glaucoma and 16 (32 eyes) had no evidence of glaucoma. All patients had either anterior segment OCT, gonioscopy, or both.Results: The 43 patients with aniridia had average age of 32±17 years, and 27 (62%) were female. Anterior segment OCT and gonioscopy were recorded in 25 (58%) of the patients and 18 (42%) of the patients had gonioscopy alone. Of the 54 eyes with aniridia and glaucoma, 4 (7%) eyes in 3 patients (11%) had partial or completely closed angles. Of the 32 eyes without glaucoma, all (100%) had open angles. The proportion of open angles in the aniridia with glaucoma eyes was not significantly different compared with the aniridia without glaucoma eyes (P=0.32). Of the 4 eyes with closed angles, all had a history of prior surgery for cataract, glaucoma, and/or keratopathy. The proportion of eyes with prior surgery was significantly higher in eyes with open-angle glaucoma and angle-closure glaucoma compared with eyes without glaucoma (P<0.001 and P=0.002, respectively).Conclusion: The majority of eyes with aniridia and glaucoma have open anterior chamber angles, similar to patients with aniridia without glaucoma. All eyes with aniridia and glaucoma that had closed angles had a prior history of ocular surgery.Keywords: aniridia, glaucoma, anterior segment optical coherence tomography (OCT), gonioscopyBajwa ABurstein EGrainger RMNetland PADove Medical Pressarticleaniridiaglaucomaanterior segment optical coherence tomography (OCT)gonioscopyOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 13, Pp 1469-1473 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	aniridia glaucoma anterior segment optical coherence tomography (OCT) gonioscopy Ophthalmology RE1-994
spellingShingle	aniridia glaucoma anterior segment optical coherence tomography (OCT) gonioscopy Ophthalmology RE1-994 Bajwa A Burstein E Grainger RM Netland PA Anterior chamber angle in aniridia with and without glaucoma
description	Asima Bajwa,1 Eitan Burstein,1 Robert M Grainger,1,2 Peter A Netland11Department of Ophthalmology, University of Virginia School of Medicine, Charlottesville, VA, USA; 2Department of Biology, University of Virginia, Charlottesville, VA, USAPurpose: We performed a retrospective, comparative study to determine if patients with aniridia and glaucoma had open angles on high-resolution anterior segment optical coherence tomography (OCT) and clinical gonioscopy.Patients and methods: Forty-three patients (86 eyes) with aniridia had recorded anterior segment OCTs, gonioscopy, or both. Of these patients, 27 (54 eyes) were diagnosed with glaucoma and 16 (32 eyes) had no evidence of glaucoma. All patients had either anterior segment OCT, gonioscopy, or both.Results: The 43 patients with aniridia had average age of 32±17 years, and 27 (62%) were female. Anterior segment OCT and gonioscopy were recorded in 25 (58%) of the patients and 18 (42%) of the patients had gonioscopy alone. Of the 54 eyes with aniridia and glaucoma, 4 (7%) eyes in 3 patients (11%) had partial or completely closed angles. Of the 32 eyes without glaucoma, all (100%) had open angles. The proportion of open angles in the aniridia with glaucoma eyes was not significantly different compared with the aniridia without glaucoma eyes (P=0.32). Of the 4 eyes with closed angles, all had a history of prior surgery for cataract, glaucoma, and/or keratopathy. The proportion of eyes with prior surgery was significantly higher in eyes with open-angle glaucoma and angle-closure glaucoma compared with eyes without glaucoma (P<0.001 and P=0.002, respectively).Conclusion: The majority of eyes with aniridia and glaucoma have open anterior chamber angles, similar to patients with aniridia without glaucoma. All eyes with aniridia and glaucoma that had closed angles had a prior history of ocular surgery.Keywords: aniridia, glaucoma, anterior segment optical coherence tomography (OCT), gonioscopy
format	article
author	Bajwa A Burstein E Grainger RM Netland PA
author_facet	Bajwa A Burstein E Grainger RM Netland PA
author_sort	Bajwa A
title	Anterior chamber angle in aniridia with and without glaucoma
title_short	Anterior chamber angle in aniridia with and without glaucoma
title_full	Anterior chamber angle in aniridia with and without glaucoma
title_fullStr	Anterior chamber angle in aniridia with and without glaucoma
title_full_unstemmed	Anterior chamber angle in aniridia with and without glaucoma
title_sort	anterior chamber angle in aniridia with and without glaucoma
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/13287a9ed76b485eb52603c4da25f203
work_keys_str_mv	AT bajwaa anteriorchamberangleinaniridiawithandwithoutglaucoma AT bursteine anteriorchamberangleinaniridiawithandwithoutglaucoma AT graingerrm anteriorchamberangleinaniridiawithandwithoutglaucoma AT netlandpa anteriorchamberangleinaniridiawithandwithoutglaucoma
_version_	1718398049356611584

Anterior chamber angle in aniridia with and without glaucoma

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