Common variation in ISL1 confers genetic susceptibility for human congenital heart disease.

Common variation in ISL1 confers genetic susceptibility for human congenital heart disease.

Congenital heart disease (CHD) is the most common birth abnormality and the etiology is unknown in the overwhelming majority of cases. ISLET1 (ISL1) is a transcription factor that marks cardiac progenitor cells and generates diverse multipotent cardiovascular cell lineages. The fundamental role of I...

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Autores principales: Kristen N Stevens, Hakon Hakonarson, Cecilia E Kim, Pieter A Doevendans, Bobby P C Koeleman, Seema Mital, Jennifer Raue, Joseph T Glessner, John G Coles, Victor Moreno, Anne Granger, Stephen B Gruber, Peter J Gruber
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/132bd25ef1cd45e7ad612e10cb094c68
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