3, 3'-Diindolylmethane enhances the effectiveness of herceptin against HER-2/neu-expressing breast cancer cells.

Herceptin failure is a major clinical problem in breast cancer. A subset of breast cancer patients with high HER-2/neu levels eventually experience metastatic disease progression when treated with Herceptin as a single agent. Mechanistic details of development of this aggressive disease are not clea...

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Autores principales: Aamir Ahmad, Shadan Ali, Alia Ahmed, Azfur S Ali, Avraham Raz, Wael A Sakr, K M Wahidur Rahman
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/132db317f8b44411888892d7b099a6a9
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