Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures
Understanding of the mycobacterial transcription system is useful to the development of therapeutics against tuberculosis infection. Here the authors present the crystal structure of a completeM. smegmatisRNA polymerase open promoter complex that reveals unique features of the mycobacterial polymera...
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Nature Portfolio
2017
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oai:doaj.org-article:133287ec42704d49bf169ec537d59a2a2021-12-02T14:42:38ZStructural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures10.1038/ncomms160722041-1723https://doaj.org/article/133287ec42704d49bf169ec537d59a2a2017-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms16072https://doaj.org/toc/2041-1723Understanding of the mycobacterial transcription system is useful to the development of therapeutics against tuberculosis infection. Here the authors present the crystal structure of a completeM. smegmatisRNA polymerase open promoter complex that reveals unique features of the mycobacterial polymerase.Elizabeth A. HubinMirjana LilicSeth A. DarstElizabeth A. CampbellNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017) |
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Science Q |
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Science Q Elizabeth A. Hubin Mirjana Lilic Seth A. Darst Elizabeth A. Campbell Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures |
description |
Understanding of the mycobacterial transcription system is useful to the development of therapeutics against tuberculosis infection. Here the authors present the crystal structure of a completeM. smegmatisRNA polymerase open promoter complex that reveals unique features of the mycobacterial polymerase. |
format |
article |
author |
Elizabeth A. Hubin Mirjana Lilic Seth A. Darst Elizabeth A. Campbell |
author_facet |
Elizabeth A. Hubin Mirjana Lilic Seth A. Darst Elizabeth A. Campbell |
author_sort |
Elizabeth A. Hubin |
title |
Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures |
title_short |
Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures |
title_full |
Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures |
title_fullStr |
Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures |
title_full_unstemmed |
Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures |
title_sort |
structural insights into the mycobacteria transcription initiation complex from analysis of x-ray crystal structures |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/133287ec42704d49bf169ec537d59a2a |
work_keys_str_mv |
AT elizabethahubin structuralinsightsintothemycobacteriatranscriptioninitiationcomplexfromanalysisofxraycrystalstructures AT mirjanalilic structuralinsightsintothemycobacteriatranscriptioninitiationcomplexfromanalysisofxraycrystalstructures AT sethadarst structuralinsightsintothemycobacteriatranscriptioninitiationcomplexfromanalysisofxraycrystalstructures AT elizabethacampbell structuralinsightsintothemycobacteriatranscriptioninitiationcomplexfromanalysisofxraycrystalstructures |
_version_ |
1718389613079298048 |