The biogenesis and function of nucleosome arrays

The biogenesis and function of nucleosome arrays

Nucleosomes form arrays with even spacing between them in virtually all eukaryotes; however, their biogenesis is incompletely understood. Here the authors show that nucleosome density and DNA sequence along with the Ino80 chromatin remodeling complex play a role in nucleosome array formation in yeas...

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Auteurs principaux: Ashish Kumar Singh, Tamás Schauer, Lena Pfaller, Tobias Straub, Felix Mueller-Planitz
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Science
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Accès en ligne:https://doaj.org/article/1332f29d056543b9b2403d11cdcdea43
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spelling oai:doaj.org-article:1332f29d056543b9b2403d11cdcdea432021-12-05T12:22:51ZThe biogenesis and function of nucleosome arrays10.1038/s41467-021-27285-62041-1723https://doaj.org/article/1332f29d056543b9b2403d11cdcdea432021-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27285-6https://doaj.org/toc/2041-1723Nucleosomes form arrays with even spacing between them in virtually all eukaryotes; however, their biogenesis is incompletely understood. Here the authors show that nucleosome density and DNA sequence along with the Ino80 chromatin remodeling complex play a role in nucleosome array formation in yeast and that the transcriptional machinery disrupts evenly-spaced nucleosomes.Ashish Kumar SinghTamás SchauerLena PfallerTobias StraubFelix Mueller-PlanitzNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ashish Kumar Singh
Tamás Schauer
Lena Pfaller
Tobias Straub
Felix Mueller-Planitz
The biogenesis and function of nucleosome arrays
description Nucleosomes form arrays with even spacing between them in virtually all eukaryotes; however, their biogenesis is incompletely understood. Here the authors show that nucleosome density and DNA sequence along with the Ino80 chromatin remodeling complex play a role in nucleosome array formation in yeast and that the transcriptional machinery disrupts evenly-spaced nucleosomes.
format article
author Ashish Kumar Singh
Tamás Schauer
Lena Pfaller
Tobias Straub
Felix Mueller-Planitz
author_facet Ashish Kumar Singh
Tamás Schauer
Lena Pfaller
Tobias Straub
Felix Mueller-Planitz
author_sort Ashish Kumar Singh
title The biogenesis and function of nucleosome arrays
title_short The biogenesis and function of nucleosome arrays
title_full The biogenesis and function of nucleosome arrays
title_fullStr The biogenesis and function of nucleosome arrays
title_full_unstemmed The biogenesis and function of nucleosome arrays
title_sort biogenesis and function of nucleosome arrays
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/1332f29d056543b9b2403d11cdcdea43
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AT tamasschauer biogenesisandfunctionofnucleosomearrays
AT lenapfaller biogenesisandfunctionofnucleosomearrays
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