The effects of death and post-mortem cold ischemia on human tissue transcriptomes
RNA levels in post-mortem tissue can differ greatly from those before death. Studying the effect of post-mortem interval on the transcriptome in 36 human tissues, Ferreira et al. find that the response to death is largely tissue-specific and develop a model to predict time since death based on RNA d...
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2018
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/13343239598e4a75b47fcf977d2aa96c |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:13343239598e4a75b47fcf977d2aa96c |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:13343239598e4a75b47fcf977d2aa96c2021-12-02T14:39:44ZThe effects of death and post-mortem cold ischemia on human tissue transcriptomes10.1038/s41467-017-02772-x2041-1723https://doaj.org/article/13343239598e4a75b47fcf977d2aa96c2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02772-xhttps://doaj.org/toc/2041-1723RNA levels in post-mortem tissue can differ greatly from those before death. Studying the effect of post-mortem interval on the transcriptome in 36 human tissues, Ferreira et al. find that the response to death is largely tissue-specific and develop a model to predict time since death based on RNA data.Pedro G. FerreiraManuel Muñoz-AguirreFerran ReverterCaio P. Sá GodinhoAbel SousaAlicia AmadozReza SodaeiMarta R. HidalgoDmitri PervouchineJose Carbonell-CaballeroRamil NurtdinovAlessandra BreschiRaziel AmadorPatrícia OliveiraCankut ÇubukJoão CuradoFrançois AguetCarla OliveiraJoaquin DopazoMichael SammethKristin G. ArdlieRoderic GuigóNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Pedro G. Ferreira Manuel Muñoz-Aguirre Ferran Reverter Caio P. Sá Godinho Abel Sousa Alicia Amadoz Reza Sodaei Marta R. Hidalgo Dmitri Pervouchine Jose Carbonell-Caballero Ramil Nurtdinov Alessandra Breschi Raziel Amador Patrícia Oliveira Cankut Çubuk João Curado François Aguet Carla Oliveira Joaquin Dopazo Michael Sammeth Kristin G. Ardlie Roderic Guigó The effects of death and post-mortem cold ischemia on human tissue transcriptomes |
| description |
RNA levels in post-mortem tissue can differ greatly from those before death. Studying the effect of post-mortem interval on the transcriptome in 36 human tissues, Ferreira et al. find that the response to death is largely tissue-specific and develop a model to predict time since death based on RNA data. |
| format |
article |
| author |
Pedro G. Ferreira Manuel Muñoz-Aguirre Ferran Reverter Caio P. Sá Godinho Abel Sousa Alicia Amadoz Reza Sodaei Marta R. Hidalgo Dmitri Pervouchine Jose Carbonell-Caballero Ramil Nurtdinov Alessandra Breschi Raziel Amador Patrícia Oliveira Cankut Çubuk João Curado François Aguet Carla Oliveira Joaquin Dopazo Michael Sammeth Kristin G. Ardlie Roderic Guigó |
| author_facet |
Pedro G. Ferreira Manuel Muñoz-Aguirre Ferran Reverter Caio P. Sá Godinho Abel Sousa Alicia Amadoz Reza Sodaei Marta R. Hidalgo Dmitri Pervouchine Jose Carbonell-Caballero Ramil Nurtdinov Alessandra Breschi Raziel Amador Patrícia Oliveira Cankut Çubuk João Curado François Aguet Carla Oliveira Joaquin Dopazo Michael Sammeth Kristin G. Ardlie Roderic Guigó |
| author_sort |
Pedro G. Ferreira |
| title |
The effects of death and post-mortem cold ischemia on human tissue transcriptomes |
| title_short |
The effects of death and post-mortem cold ischemia on human tissue transcriptomes |
| title_full |
The effects of death and post-mortem cold ischemia on human tissue transcriptomes |
| title_fullStr |
The effects of death and post-mortem cold ischemia on human tissue transcriptomes |
| title_full_unstemmed |
The effects of death and post-mortem cold ischemia on human tissue transcriptomes |
| title_sort |
effects of death and post-mortem cold ischemia on human tissue transcriptomes |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/13343239598e4a75b47fcf977d2aa96c |
| work_keys_str_mv |
AT pedrogferreira theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT manuelmunozaguirre theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT ferranreverter theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT caiopsagodinho theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT abelsousa theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT aliciaamadoz theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT rezasodaei theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT martarhidalgo theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT dmitripervouchine theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT josecarbonellcaballero theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT ramilnurtdinov theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT alessandrabreschi theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT razielamador theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT patriciaoliveira theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT cankutcubuk theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT joaocurado theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT francoisaguet theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT carlaoliveira theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT joaquindopazo theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT michaelsammeth theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT kristingardlie theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT rodericguigo theeffectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT pedrogferreira effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT manuelmunozaguirre effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT ferranreverter effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT caiopsagodinho effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT abelsousa effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT aliciaamadoz effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT rezasodaei effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT martarhidalgo effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT dmitripervouchine effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT josecarbonellcaballero effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT ramilnurtdinov effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT alessandrabreschi effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT razielamador effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT patriciaoliveira effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT cankutcubuk effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT joaocurado effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT francoisaguet effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT carlaoliveira effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT joaquindopazo effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT michaelsammeth effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT kristingardlie effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes AT rodericguigo effectsofdeathandpostmortemcoldischemiaonhumantissuetranscriptomes |
| _version_ |
1718390518625337344 |