Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses

Treatment of influenza A viruses with broadly neutralizing monoclonal antibodies is an area of active research. Here, the authors characterise a human monoclonal antibody called 3E1 that was reactive against both H1 and H5 viruses in vitroand demonstrated some treatment efficacy in mice.

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Autores principales:	Wenshuai Wang, Xiaoyu Sun, Yanbing Li, Jinpeng Su, Zhiyang Ling, Tianlong Zhang, Fang Wang, Hong Zhang, Hualan Chen, Jianping Ding, Bing Sun
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/133592a173724d4893bab2f4f11b4436
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spelling	oai:doaj.org-article:133592a173724d4893bab2f4f11b44362021-12-02T17:32:19ZHuman antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses10.1038/ncomms135772041-1723https://doaj.org/article/133592a173724d4893bab2f4f11b44362016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13577https://doaj.org/toc/2041-1723Treatment of influenza A viruses with broadly neutralizing monoclonal antibodies is an area of active research. Here, the authors characterise a human monoclonal antibody called 3E1 that was reactive against both H1 and H5 viruses in vitroand demonstrated some treatment efficacy in mice.Wenshuai WangXiaoyu SunYanbing LiJinpeng SuZhiyang LingTianlong ZhangFang WangHong ZhangHualan ChenJianping DingBing SunNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wenshuai Wang Xiaoyu Sun Yanbing Li Jinpeng Su Zhiyang Ling Tianlong Zhang Fang Wang Hong Zhang Hualan Chen Jianping Ding Bing Sun Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses
description	Treatment of influenza A viruses with broadly neutralizing monoclonal antibodies is an area of active research. Here, the authors characterise a human monoclonal antibody called 3E1 that was reactive against both H1 and H5 viruses in vitroand demonstrated some treatment efficacy in mice.
format	article
author	Wenshuai Wang Xiaoyu Sun Yanbing Li Jinpeng Su Zhiyang Ling Tianlong Zhang Fang Wang Hong Zhang Hualan Chen Jianping Ding Bing Sun
author_facet	Wenshuai Wang Xiaoyu Sun Yanbing Li Jinpeng Su Zhiyang Ling Tianlong Zhang Fang Wang Hong Zhang Hualan Chen Jianping Ding Bing Sun
author_sort	Wenshuai Wang
title	Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses
title_short	Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses
title_full	Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses
title_fullStr	Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses
title_full_unstemmed	Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses
title_sort	human antibody 3e1 targets the ha stem region of h1n1 and h5n6 influenza a viruses
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/133592a173724d4893bab2f4f11b4436
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Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses

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