N-aryl pyrido cyanine derivatives are nuclear and organelle DNA markers for two-photon and super-resolution imaging

It is challenging to develop DNA probes that allow staining of both organelle and nuclear DNA, are compatible with super resolution imaging and avoid UV-light photo-excitation. The authors overcome these issues with N-aryl pyrido cyanine derivatives showing high DNA specificity and membrane permeabi...

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Autores principales:	Kakishi Uno, Nagisa Sugimoto, Yoshikatsu Sato
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1336b3fa925c4afa8e360825b534695f
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id	oai:doaj.org-article:1336b3fa925c4afa8e360825b534695f
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spelling	oai:doaj.org-article:1336b3fa925c4afa8e360825b534695f2021-12-02T14:35:46ZN-aryl pyrido cyanine derivatives are nuclear and organelle DNA markers for two-photon and super-resolution imaging10.1038/s41467-021-23019-w2041-1723https://doaj.org/article/1336b3fa925c4afa8e360825b534695f2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23019-whttps://doaj.org/toc/2041-1723It is challenging to develop DNA probes that allow staining of both organelle and nuclear DNA, are compatible with super resolution imaging and avoid UV-light photo-excitation. The authors overcome these issues with N-aryl pyrido cyanine derivatives showing high DNA specificity and membrane permeability.Kakishi UnoNagisa SugimotoYoshikatsu SatoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kakishi Uno Nagisa Sugimoto Yoshikatsu Sato N-aryl pyrido cyanine derivatives are nuclear and organelle DNA markers for two-photon and super-resolution imaging
description	It is challenging to develop DNA probes that allow staining of both organelle and nuclear DNA, are compatible with super resolution imaging and avoid UV-light photo-excitation. The authors overcome these issues with N-aryl pyrido cyanine derivatives showing high DNA specificity and membrane permeability.
format	article
author	Kakishi Uno Nagisa Sugimoto Yoshikatsu Sato
author_facet	Kakishi Uno Nagisa Sugimoto Yoshikatsu Sato
author_sort	Kakishi Uno
title	N-aryl pyrido cyanine derivatives are nuclear and organelle DNA markers for two-photon and super-resolution imaging
title_short	N-aryl pyrido cyanine derivatives are nuclear and organelle DNA markers for two-photon and super-resolution imaging
title_full	N-aryl pyrido cyanine derivatives are nuclear and organelle DNA markers for two-photon and super-resolution imaging
title_fullStr	N-aryl pyrido cyanine derivatives are nuclear and organelle DNA markers for two-photon and super-resolution imaging
title_full_unstemmed	N-aryl pyrido cyanine derivatives are nuclear and organelle DNA markers for two-photon and super-resolution imaging
title_sort	n-aryl pyrido cyanine derivatives are nuclear and organelle dna markers for two-photon and super-resolution imaging
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1336b3fa925c4afa8e360825b534695f
work_keys_str_mv	AT kakishiuno narylpyridocyaninederivativesarenuclearandorganellednamarkersfortwophotonandsuperresolutionimaging AT nagisasugimoto narylpyridocyaninederivativesarenuclearandorganellednamarkersfortwophotonandsuperresolutionimaging AT yoshikatsusato narylpyridocyaninederivativesarenuclearandorganellednamarkersfortwophotonandsuperresolutionimaging
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N-aryl pyrido cyanine derivatives are nuclear and organelle DNA markers for two-photon and super-resolution imaging

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