Three-dimensional tomosynthesis versus two-dimensional mammography in detection and characterization of different breast lesions

Abstract Background Breast cancer is considered the most serious lesion among different breast lesions. Mammography is the corner stone for screening for detection of breast cancer. It has been modified to digital mammography (DM) and then to digital breast tomosynthesis (DBT). Tomosynthesis is an e...

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Autores principales:	Samia Aboelnour Abdeltwab Abdelattef, Suzan Farouk Ibrahim, Wafaa Raft Abdelhamid, Fatten Mohamed Mahmoud
Formato:	article
Lenguaje:	EN
Publicado:	SpringerOpen 2021
Materias:	Breast lesions Digital mammography Digital tomosynthesis Medical physics. Medical radiology. Nuclear medicine R895-920
Acceso en línea:	https://doaj.org/article/1338be674c3b4017ad5fc877df596436
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spelling	oai:doaj.org-article:1338be674c3b4017ad5fc877df5964362021-11-14T12:27:08ZThree-dimensional tomosynthesis versus two-dimensional mammography in detection and characterization of different breast lesions10.1186/s43055-021-00648-12090-4762https://doaj.org/article/1338be674c3b4017ad5fc877df5964362021-11-01T00:00:00Zhttps://doi.org/10.1186/s43055-021-00648-1https://doaj.org/toc/2090-4762Abstract Background Breast cancer is considered the most serious lesion among different breast lesions. Mammography is the corner stone for screening for detection of breast cancer. It has been modified to digital mammography (DM) and then to digital breast tomosynthesis (DBT). Tomosynthesis is an emerging technique for diagnosis and screening of breast lesions. The aim of this study is to interrogate whether the addition of DBT to DM helps in better detection and characterization of different breast lesions. Methods This is a prospective study carried on 38 female patients according to our inclusion criteria. All patients were evaluated by using DM alone and thereafter with the addition of DBT to DM. Recall rate was calculated, and the imaging findings of each case were correlated with the final diagnosis and follow-up. Results DM identified 32 lesions while DBT with DM identified 37 lesions. On DM alone, 17 lesions were characterized as masses, 5 as focal asymmetry, 2 as architectural distortion, 7 as microcalcification and 1 as macrocalcification. With the addition of DBT, 27 lesions were characterized as masses, 1 as focal asymmetry, 1 as architectural distortion, 7 as microcalcification and 1 as macrocalcification. So, there were better detection and characterization of lesions with the addition of DBT than DM alone. The sensitivity, specificity, AUC, positive and negative predictive values were significantly higher with the addition of DBT to DM (100%, 90.5%, 0.952, 90% and 100%, respectively) than with DM (77.8%, 80.9%, 0.794, 77.8% and 80.9%, respectively) for all breast lesions. Conclusions The addition of DBT to DM helps in better detection and characterization of different breast lesions. This leads to early detection of breast cancer, improvement of the performance of radiologists and saving time by reduction of recall rate.Samia Aboelnour Abdeltwab AbdelattefSuzan Farouk IbrahimWafaa Raft AbdelhamidFatten Mohamed MahmoudSpringerOpenarticleBreast lesionsDigital mammographyDigital tomosynthesisMedical physics. Medical radiology. Nuclear medicineR895-920ENThe Egyptian Journal of Radiology and Nuclear Medicine, Vol 52, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Breast lesions Digital mammography Digital tomosynthesis Medical physics. Medical radiology. Nuclear medicine R895-920
spellingShingle	Breast lesions Digital mammography Digital tomosynthesis Medical physics. Medical radiology. Nuclear medicine R895-920 Samia Aboelnour Abdeltwab Abdelattef Suzan Farouk Ibrahim Wafaa Raft Abdelhamid Fatten Mohamed Mahmoud Three-dimensional tomosynthesis versus two-dimensional mammography in detection and characterization of different breast lesions
description	Abstract Background Breast cancer is considered the most serious lesion among different breast lesions. Mammography is the corner stone for screening for detection of breast cancer. It has been modified to digital mammography (DM) and then to digital breast tomosynthesis (DBT). Tomosynthesis is an emerging technique for diagnosis and screening of breast lesions. The aim of this study is to interrogate whether the addition of DBT to DM helps in better detection and characterization of different breast lesions. Methods This is a prospective study carried on 38 female patients according to our inclusion criteria. All patients were evaluated by using DM alone and thereafter with the addition of DBT to DM. Recall rate was calculated, and the imaging findings of each case were correlated with the final diagnosis and follow-up. Results DM identified 32 lesions while DBT with DM identified 37 lesions. On DM alone, 17 lesions were characterized as masses, 5 as focal asymmetry, 2 as architectural distortion, 7 as microcalcification and 1 as macrocalcification. With the addition of DBT, 27 lesions were characterized as masses, 1 as focal asymmetry, 1 as architectural distortion, 7 as microcalcification and 1 as macrocalcification. So, there were better detection and characterization of lesions with the addition of DBT than DM alone. The sensitivity, specificity, AUC, positive and negative predictive values were significantly higher with the addition of DBT to DM (100%, 90.5%, 0.952, 90% and 100%, respectively) than with DM (77.8%, 80.9%, 0.794, 77.8% and 80.9%, respectively) for all breast lesions. Conclusions The addition of DBT to DM helps in better detection and characterization of different breast lesions. This leads to early detection of breast cancer, improvement of the performance of radiologists and saving time by reduction of recall rate.
format	article
author	Samia Aboelnour Abdeltwab Abdelattef Suzan Farouk Ibrahim Wafaa Raft Abdelhamid Fatten Mohamed Mahmoud
author_facet	Samia Aboelnour Abdeltwab Abdelattef Suzan Farouk Ibrahim Wafaa Raft Abdelhamid Fatten Mohamed Mahmoud
author_sort	Samia Aboelnour Abdeltwab Abdelattef
title	Three-dimensional tomosynthesis versus two-dimensional mammography in detection and characterization of different breast lesions
title_short	Three-dimensional tomosynthesis versus two-dimensional mammography in detection and characterization of different breast lesions
title_full	Three-dimensional tomosynthesis versus two-dimensional mammography in detection and characterization of different breast lesions
title_fullStr	Three-dimensional tomosynthesis versus two-dimensional mammography in detection and characterization of different breast lesions
title_full_unstemmed	Three-dimensional tomosynthesis versus two-dimensional mammography in detection and characterization of different breast lesions
title_sort	three-dimensional tomosynthesis versus two-dimensional mammography in detection and characterization of different breast lesions
publisher	SpringerOpen
publishDate	2021
url	https://doaj.org/article/1338be674c3b4017ad5fc877df596436
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Three-dimensional tomosynthesis versus two-dimensional mammography in detection and characterization of different breast lesions

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