Depression in Heart Failure: Psychosomatic Approach

Depression is a common condition in heart failure (HF) and is considered a risk factor for cardiovascular disease. Depression disorder in patients with heart disease paradigmatically defines a psychosomatic-somatopsychic challenge to any health delivery. However, despite the devastating effects of d...

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Autores principales: Rudi Putranto, Hamzah Shatri, Ika Prasetya Wijaya, Edward Faisal
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Publicado: Department of Internal Medicine, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo Hospital 2021
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Acceso en línea:http://dx.doi.org/10.7454/jpdi.v8i3.182
https://doaj.org/article/133d01fef2a84a15ab17e8de71a2da8c
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spelling oai:doaj.org-article:133d01fef2a84a15ab17e8de71a2da8c2021-11-17T14:09:41ZDepression in Heart Failure: Psychosomatic Approachhttp://dx.doi.org/10.7454/jpdi.v8i3.1822406-89692549-0621https://doaj.org/article/133d01fef2a84a15ab17e8de71a2da8c2021-09-01T00:00:00Zhttp://jurnalpenyakitdalam.ui.ac.id/index.php/jpdi/article/view/182/281https://doaj.org/toc/2406-8969https://doaj.org/toc/2549-0621Depression is a common condition in heart failure (HF) and is considered a risk factor for cardiovascular disease. Depression disorder in patients with heart disease paradigmatically defines a psychosomatic-somatopsychic challenge to any health delivery. However, despite the devastating effects of depression, it is often underdiagnosed and receives little attention in heart failure patients. This review provides an extensive overview of HF regarding epidemiology, disease pathophysiology, diagnosis, and management from the latest literature. Based on the literature review, the prevalence of depression in heart failure in Indonesian patients was 5.3-42%. Psychological stress experienced by people suffering from depression can cause dysregulation in the sympathetic nervous system and hypothalamic–pituitary–adrenal (HPA) axis. This mechanism, in turn, has some deleterious downstream effects, including the development of hypertension, left ventricular hypertrophy, coronary vasoconstriction, endothelial dysfunction, platelet activation, and the production of pro-inflammatory cytokines. The Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5), published by the American Psychiatric Association, is used to diagnose depression in patients with HF. Meanwhile, the Patient Health Questionnaire (PHQ)-2 and PHQ-9 are commonly used as screening tools for depression in patients with HF. The Biopsychosocial-spiritual model as a psychosomatic approach have might reduce or prevent depression and thus improve quality of life and other outcomes. Evidence reveals that both psychotherapeutic treatment (e.g., cognitive-behavioral therapy) and pharmacologic treatment (e.g., use of the selective serotonin reuptake inhibitor sertraline) are safe and effective in managing depression in patients with cardiovascular disease. In conclusion, the review of articles in this paper shows that there is a high prevalence of depression in heart failure, but it is often not recognized by doctors, there is a relationship between psychosomatic, and heart failure, non-pharmacological interventions such as psychotherapy and pharmacological therapy have benefits. Future research is needed to create evidence-based evaluations and treatment algorithms tailored to the specific needs of the target population.Rudi PutrantoHamzah ShatriIka Prasetya WijayaEdward FaisalDepartment of Internal Medicine, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo Hospitalarticledepressiondiagnosisheart failurepsychosomaticInternal medicineRC31-1245IDJurnal Penyakit Dalam Indonesia, Vol 8, Iss 3, Pp 154-160 (2021)
institution DOAJ
collection DOAJ
language ID
topic depression
diagnosis
heart failure
psychosomatic
Internal medicine
RC31-1245
spellingShingle depression
diagnosis
heart failure
psychosomatic
Internal medicine
RC31-1245
Rudi Putranto
Hamzah Shatri
Ika Prasetya Wijaya
Edward Faisal
Depression in Heart Failure: Psychosomatic Approach
description Depression is a common condition in heart failure (HF) and is considered a risk factor for cardiovascular disease. Depression disorder in patients with heart disease paradigmatically defines a psychosomatic-somatopsychic challenge to any health delivery. However, despite the devastating effects of depression, it is often underdiagnosed and receives little attention in heart failure patients. This review provides an extensive overview of HF regarding epidemiology, disease pathophysiology, diagnosis, and management from the latest literature. Based on the literature review, the prevalence of depression in heart failure in Indonesian patients was 5.3-42%. Psychological stress experienced by people suffering from depression can cause dysregulation in the sympathetic nervous system and hypothalamic–pituitary–adrenal (HPA) axis. This mechanism, in turn, has some deleterious downstream effects, including the development of hypertension, left ventricular hypertrophy, coronary vasoconstriction, endothelial dysfunction, platelet activation, and the production of pro-inflammatory cytokines. The Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5), published by the American Psychiatric Association, is used to diagnose depression in patients with HF. Meanwhile, the Patient Health Questionnaire (PHQ)-2 and PHQ-9 are commonly used as screening tools for depression in patients with HF. The Biopsychosocial-spiritual model as a psychosomatic approach have might reduce or prevent depression and thus improve quality of life and other outcomes. Evidence reveals that both psychotherapeutic treatment (e.g., cognitive-behavioral therapy) and pharmacologic treatment (e.g., use of the selective serotonin reuptake inhibitor sertraline) are safe and effective in managing depression in patients with cardiovascular disease. In conclusion, the review of articles in this paper shows that there is a high prevalence of depression in heart failure, but it is often not recognized by doctors, there is a relationship between psychosomatic, and heart failure, non-pharmacological interventions such as psychotherapy and pharmacological therapy have benefits. Future research is needed to create evidence-based evaluations and treatment algorithms tailored to the specific needs of the target population.
format article
author Rudi Putranto
Hamzah Shatri
Ika Prasetya Wijaya
Edward Faisal
author_facet Rudi Putranto
Hamzah Shatri
Ika Prasetya Wijaya
Edward Faisal
author_sort Rudi Putranto
title Depression in Heart Failure: Psychosomatic Approach
title_short Depression in Heart Failure: Psychosomatic Approach
title_full Depression in Heart Failure: Psychosomatic Approach
title_fullStr Depression in Heart Failure: Psychosomatic Approach
title_full_unstemmed Depression in Heart Failure: Psychosomatic Approach
title_sort depression in heart failure: psychosomatic approach
publisher Department of Internal Medicine, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo Hospital
publishDate 2021
url http://dx.doi.org/10.7454/jpdi.v8i3.182
https://doaj.org/article/133d01fef2a84a15ab17e8de71a2da8c
work_keys_str_mv AT rudiputranto depressioninheartfailurepsychosomaticapproach
AT hamzahshatri depressioninheartfailurepsychosomaticapproach
AT ikaprasetyawijaya depressioninheartfailurepsychosomaticapproach
AT edwardfaisal depressioninheartfailurepsychosomaticapproach
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