Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1
Hundreds of mRNA binding proteins (mRBPs) have been described in mammalian cells. Here, the authors identify RBPs differentially regulated in melanoma, and show the RBP CELF1 controlling a distinct set of protumorigenic factors.
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Nature Portfolio
2017
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oai:doaj.org-article:1340379aab9748ac8e9ce5a84d0a223c2021-12-02T15:38:53ZSystems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF110.1038/s41467-017-02353-y2041-1723https://doaj.org/article/1340379aab9748ac8e9ce5a84d0a223c2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02353-yhttps://doaj.org/toc/2041-1723Hundreds of mRNA binding proteins (mRBPs) have been described in mammalian cells. Here, the authors identify RBPs differentially regulated in melanoma, and show the RBP CELF1 controlling a distinct set of protumorigenic factors.Metehan CifdalozLisa OsterlohOsvaldo GrañaErica Riveiro-FalkenbachPilar Ximénez-EmbúnJavier MuñozCristina TejedoTonantzin G. CalvoPanagiotis KarrasDavid OlmedaBelén MiñanaGonzalo Gómez-LópezEstela CañonEduardo EyrasHaihong GuoFerdinand KappesPablo L. Ortiz-RomeroJose L. Rodríguez-PeraltoDiego MegíasJuan ValcárcelMaría S. SoengasNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-18 (2017) |
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Science Q Metehan Cifdaloz Lisa Osterloh Osvaldo Graña Erica Riveiro-Falkenbach Pilar Ximénez-Embún Javier Muñoz Cristina Tejedo Tonantzin G. Calvo Panagiotis Karras David Olmeda Belén Miñana Gonzalo Gómez-López Estela Cañon Eduardo Eyras Haihong Guo Ferdinand Kappes Pablo L. Ortiz-Romero Jose L. Rodríguez-Peralto Diego Megías Juan Valcárcel María S. Soengas Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1 |
| description |
Hundreds of mRNA binding proteins (mRBPs) have been described in mammalian cells. Here, the authors identify RBPs differentially regulated in melanoma, and show the RBP CELF1 controlling a distinct set of protumorigenic factors. |
| format |
article |
| author |
Metehan Cifdaloz Lisa Osterloh Osvaldo Graña Erica Riveiro-Falkenbach Pilar Ximénez-Embún Javier Muñoz Cristina Tejedo Tonantzin G. Calvo Panagiotis Karras David Olmeda Belén Miñana Gonzalo Gómez-López Estela Cañon Eduardo Eyras Haihong Guo Ferdinand Kappes Pablo L. Ortiz-Romero Jose L. Rodríguez-Peralto Diego Megías Juan Valcárcel María S. Soengas |
| author_facet |
Metehan Cifdaloz Lisa Osterloh Osvaldo Graña Erica Riveiro-Falkenbach Pilar Ximénez-Embún Javier Muñoz Cristina Tejedo Tonantzin G. Calvo Panagiotis Karras David Olmeda Belén Miñana Gonzalo Gómez-López Estela Cañon Eduardo Eyras Haihong Guo Ferdinand Kappes Pablo L. Ortiz-Romero Jose L. Rodríguez-Peralto Diego Megías Juan Valcárcel María S. Soengas |
| author_sort |
Metehan Cifdaloz |
| title |
Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1 |
| title_short |
Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1 |
| title_full |
Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1 |
| title_fullStr |
Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1 |
| title_full_unstemmed |
Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1 |
| title_sort |
systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the rna binding protein celf1 |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/1340379aab9748ac8e9ce5a84d0a223c |
| work_keys_str_mv |
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