Thiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis

When grown in the lab, Mycobacterium tuberculosis can form pellicle biofilms. Here, Trivedi et al. show that thiol reductive stress (induced by dithiothreitol) triggers rapid formation of thicker biofilms containing cellulose as well as antibiotic-tolerant, metabolically active bacteria.

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Autores principales: Abhishek Trivedi, Parminder Singh Mavi, Deepak Bhatt, Ashwani Kumar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/1343f01915784f148e9099618582fc79
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spelling oai:doaj.org-article:1343f01915784f148e9099618582fc792021-12-02T15:34:08ZThiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis10.1038/ncomms113922041-1723https://doaj.org/article/1343f01915784f148e9099618582fc792016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11392https://doaj.org/toc/2041-1723When grown in the lab, Mycobacterium tuberculosis can form pellicle biofilms. Here, Trivedi et al. show that thiol reductive stress (induced by dithiothreitol) triggers rapid formation of thicker biofilms containing cellulose as well as antibiotic-tolerant, metabolically active bacteria.Abhishek TrivediParminder Singh MaviDeepak BhattAshwani KumarNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Abhishek Trivedi
Parminder Singh Mavi
Deepak Bhatt
Ashwani Kumar
Thiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis
description When grown in the lab, Mycobacterium tuberculosis can form pellicle biofilms. Here, Trivedi et al. show that thiol reductive stress (induced by dithiothreitol) triggers rapid formation of thicker biofilms containing cellulose as well as antibiotic-tolerant, metabolically active bacteria.
format article
author Abhishek Trivedi
Parminder Singh Mavi
Deepak Bhatt
Ashwani Kumar
author_facet Abhishek Trivedi
Parminder Singh Mavi
Deepak Bhatt
Ashwani Kumar
author_sort Abhishek Trivedi
title Thiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis
title_short Thiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis
title_full Thiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis
title_fullStr Thiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis
title_full_unstemmed Thiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis
title_sort thiol reductive stress induces cellulose-anchored biofilm formation in mycobacterium tuberculosis
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/1343f01915784f148e9099618582fc79
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AT deepakbhatt thiolreductivestressinducescelluloseanchoredbiofilmformationinmycobacteriumtuberculosis
AT ashwanikumar thiolreductivestressinducescelluloseanchoredbiofilmformationinmycobacteriumtuberculosis
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