Synthetic photoplethysmography (PPG) of the radial artery through parallelized Monte Carlo and its correlation to body mass index (BMI)

Abstract Cardiovascular disease is one of the leading causes of death in the United States and obesity significantly increases the risk of cardiovascular disease. The measurement of blood pressure (BP) is critical in monitoring and managing cardiovascular disease hence new wearable devices are being...

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Autores principales:	Tananant Boonya-ananta, Andres J. Rodriguez, Ajmal Ajmal, Vinh Nguyen Du Le, Anders K. Hansen, Joshua D. Hutcheson, Jessica C. Ramella-Roman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/1346a1b441d542b68dcd645b511a2475
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spelling	oai:doaj.org-article:1346a1b441d542b68dcd645b511a24752021-12-02T13:57:38ZSynthetic photoplethysmography (PPG) of the radial artery through parallelized Monte Carlo and its correlation to body mass index (BMI)10.1038/s41598-021-82124-42045-2322https://doaj.org/article/1346a1b441d542b68dcd645b511a24752021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-82124-4https://doaj.org/toc/2045-2322Abstract Cardiovascular disease is one of the leading causes of death in the United States and obesity significantly increases the risk of cardiovascular disease. The measurement of blood pressure (BP) is critical in monitoring and managing cardiovascular disease hence new wearable devices are being developed to make BP more accessible to physicians and patients. Several wearables utilize photoplethysmography from the wrist vasculature to derive BP assessment although many of these devices are still at the experimental stage. With the ultimate goal of supporting instrument development, we have developed a model of the photoplethysmographic waveform derived from the radial artery at the volar surface of the wrist. To do so we have utilized the relation between vessel biomechanics through Finite Element Method and Monte Carlo light transport model. The model shows similar features to that seen in PPG waveform captured using an off the shelf device. We observe the influence of body mass index on the PPG signal. A degradation the PPG signal of up to 40% in AC to DC signal ratio was thus observed.Tananant Boonya-anantaAndres J. RodriguezAjmal AjmalVinh Nguyen Du LeAnders K. HansenJoshua D. HutchesonJessica C. Ramella-RomanNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Tananant Boonya-ananta Andres J. Rodriguez Ajmal Ajmal Vinh Nguyen Du Le Anders K. Hansen Joshua D. Hutcheson Jessica C. Ramella-Roman Synthetic photoplethysmography (PPG) of the radial artery through parallelized Monte Carlo and its correlation to body mass index (BMI)
description	Abstract Cardiovascular disease is one of the leading causes of death in the United States and obesity significantly increases the risk of cardiovascular disease. The measurement of blood pressure (BP) is critical in monitoring and managing cardiovascular disease hence new wearable devices are being developed to make BP more accessible to physicians and patients. Several wearables utilize photoplethysmography from the wrist vasculature to derive BP assessment although many of these devices are still at the experimental stage. With the ultimate goal of supporting instrument development, we have developed a model of the photoplethysmographic waveform derived from the radial artery at the volar surface of the wrist. To do so we have utilized the relation between vessel biomechanics through Finite Element Method and Monte Carlo light transport model. The model shows similar features to that seen in PPG waveform captured using an off the shelf device. We observe the influence of body mass index on the PPG signal. A degradation the PPG signal of up to 40% in AC to DC signal ratio was thus observed.
format	article
author	Tananant Boonya-ananta Andres J. Rodriguez Ajmal Ajmal Vinh Nguyen Du Le Anders K. Hansen Joshua D. Hutcheson Jessica C. Ramella-Roman
author_facet	Tananant Boonya-ananta Andres J. Rodriguez Ajmal Ajmal Vinh Nguyen Du Le Anders K. Hansen Joshua D. Hutcheson Jessica C. Ramella-Roman
author_sort	Tananant Boonya-ananta
title	Synthetic photoplethysmography (PPG) of the radial artery through parallelized Monte Carlo and its correlation to body mass index (BMI)
title_short	Synthetic photoplethysmography (PPG) of the radial artery through parallelized Monte Carlo and its correlation to body mass index (BMI)
title_full	Synthetic photoplethysmography (PPG) of the radial artery through parallelized Monte Carlo and its correlation to body mass index (BMI)
title_fullStr	Synthetic photoplethysmography (PPG) of the radial artery through parallelized Monte Carlo and its correlation to body mass index (BMI)
title_full_unstemmed	Synthetic photoplethysmography (PPG) of the radial artery through parallelized Monte Carlo and its correlation to body mass index (BMI)
title_sort	synthetic photoplethysmography (ppg) of the radial artery through parallelized monte carlo and its correlation to body mass index (bmi)
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1346a1b441d542b68dcd645b511a2475
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Synthetic photoplethysmography (PPG) of the radial artery through parallelized Monte Carlo and its correlation to body mass index (BMI)

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