The landscape of alternative polyadenylation in single cells of the developing mouse embryo
Alternative polyadenylation regulates localization, half-life and translation of mRNA isoforms. Here the authors investigate alternative polyadenylation using single cell RNA sequencing data from mouse embryos and identify 3’-UTR isoforms that are regulated across cell types and developmental time....
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Auteurs principaux: | Vikram Agarwal, Sereno Lopez-Darwin, David R. Kelley, Jay Shendure |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/134bcf57b93d4e3b8d28f9f70ad6e1af |
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