Evaluation of the Incidence of Chorionic Villus Sampling Complications at 10-13 Weeks of Gestation for Early Diagnosis of Major Thalassemia

BACKGROUND AND OBJECTIVE: Early diagnosis of thalassemia with chorionic villus sampling (CVS) has an important role in fetal evaluation. Because of increasing risk of fetal loss and other probable risks, it seems that information about the incidence of complications of this method in the mother and...

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Autores principales:	R Monzavi Sani, F Savadkuhi, Z Roohani
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2010
Materias:	chorionic villus sampling major thalassemia subchorionic hematoma abortion Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/13593b034b46405d83b6eb0b3ca93000
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spelling	oai:doaj.org-article:13593b034b46405d83b6eb0b3ca930002021-11-10T09:00:36ZEvaluation of the Incidence of Chorionic Villus Sampling Complications at 10-13 Weeks of Gestation for Early Diagnosis of Major Thalassemia1561-41072251-7170https://doaj.org/article/13593b034b46405d83b6eb0b3ca930002010-10-01T00:00:00Zhttp://jbums.org/article-1-3666-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Early diagnosis of thalassemia with chorionic villus sampling (CVS) has an important role in fetal evaluation. Because of increasing risk of fetal loss and other probable risks, it seems that information about the incidence of complications of this method in the mother and the fetus is invaluable. Therefore this study was performed to evaluate the incidence of complications of chorionic villus sampling in Sistan and Baluchestan province, Iran.METHODS: This cross sectional study was performed on 137 pregnant women (gestational age of 10-13 weeks) who referred to CVS center of Zahedan University of medical sciences, Zahedan, Iran. Transabdominal chorionic villus sampling was performed with sonographic guide. Samplings were sent to genetic laboratory. Immediately after sampling, the control sonography was performed for detecting the placental hemorrhage at the sampling site, subchorionic hematoma and fetal heart rate. The pregnant woman was discharged after 2 hours rest. Also, the final evaluation was performed on neonates to detect any defects.FINDINGS: The most common early complication of CVS was subchorionic hematomain in 9 (6.5%), that in one of these cases placental abruption was observed and abortion occurred finally. Fetal loss rate was 0.7% (1 case) and no defects were found in neonatal follow up. CONCLUSION: The results of this study show that chorionic villus sampling could be dangerous and it should be done carefully and if CVS is performed after 10 weeks of gestation, it does not increase the risk of fetal anomalies.R Monzavi SaniF SavadkuhiZ RoohaniBabol University of Medical Sciencesarticlechorionic villus samplingmajor thalassemiasubchorionic hematomaabortionMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 12, Iss 4, Pp 43-47 (2010)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	chorionic villus sampling major thalassemia subchorionic hematoma abortion Medicine R Medicine (General) R5-920
spellingShingle	chorionic villus sampling major thalassemia subchorionic hematoma abortion Medicine R Medicine (General) R5-920 R Monzavi Sani F Savadkuhi Z Roohani Evaluation of the Incidence of Chorionic Villus Sampling Complications at 10-13 Weeks of Gestation for Early Diagnosis of Major Thalassemia
description	BACKGROUND AND OBJECTIVE: Early diagnosis of thalassemia with chorionic villus sampling (CVS) has an important role in fetal evaluation. Because of increasing risk of fetal loss and other probable risks, it seems that information about the incidence of complications of this method in the mother and the fetus is invaluable. Therefore this study was performed to evaluate the incidence of complications of chorionic villus sampling in Sistan and Baluchestan province, Iran.METHODS: This cross sectional study was performed on 137 pregnant women (gestational age of 10-13 weeks) who referred to CVS center of Zahedan University of medical sciences, Zahedan, Iran. Transabdominal chorionic villus sampling was performed with sonographic guide. Samplings were sent to genetic laboratory. Immediately after sampling, the control sonography was performed for detecting the placental hemorrhage at the sampling site, subchorionic hematoma and fetal heart rate. The pregnant woman was discharged after 2 hours rest. Also, the final evaluation was performed on neonates to detect any defects.FINDINGS: The most common early complication of CVS was subchorionic hematomain in 9 (6.5%), that in one of these cases placental abruption was observed and abortion occurred finally. Fetal loss rate was 0.7% (1 case) and no defects were found in neonatal follow up. CONCLUSION: The results of this study show that chorionic villus sampling could be dangerous and it should be done carefully and if CVS is performed after 10 weeks of gestation, it does not increase the risk of fetal anomalies.
format	article
author	R Monzavi Sani F Savadkuhi Z Roohani
author_facet	R Monzavi Sani F Savadkuhi Z Roohani
author_sort	R Monzavi Sani
title	Evaluation of the Incidence of Chorionic Villus Sampling Complications at 10-13 Weeks of Gestation for Early Diagnosis of Major Thalassemia
title_short	Evaluation of the Incidence of Chorionic Villus Sampling Complications at 10-13 Weeks of Gestation for Early Diagnosis of Major Thalassemia
title_full	Evaluation of the Incidence of Chorionic Villus Sampling Complications at 10-13 Weeks of Gestation for Early Diagnosis of Major Thalassemia
title_fullStr	Evaluation of the Incidence of Chorionic Villus Sampling Complications at 10-13 Weeks of Gestation for Early Diagnosis of Major Thalassemia
title_full_unstemmed	Evaluation of the Incidence of Chorionic Villus Sampling Complications at 10-13 Weeks of Gestation for Early Diagnosis of Major Thalassemia
title_sort	evaluation of the incidence of chorionic villus sampling complications at 10-13 weeks of gestation for early diagnosis of major thalassemia
publisher	Babol University of Medical Sciences
publishDate	2010
url	https://doaj.org/article/13593b034b46405d83b6eb0b3ca93000
work_keys_str_mv	AT rmonzavisani evaluationoftheincidenceofchorionicvillussamplingcomplicationsat1013weeksofgestationforearlydiagnosisofmajorthalassemia AT fsavadkuhi evaluationoftheincidenceofchorionicvillussamplingcomplicationsat1013weeksofgestationforearlydiagnosisofmajorthalassemia AT zroohani evaluationoftheincidenceofchorionicvillussamplingcomplicationsat1013weeksofgestationforearlydiagnosisofmajorthalassemia
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Evaluation of the Incidence of Chorionic Villus Sampling Complications at 10-13 Weeks of Gestation for Early Diagnosis of Major Thalassemia

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