Origin and loss of nested LRRTM/α-catenin genes during vertebrate evolution.

Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) form in mammals a family of four postsynaptic adhesion proteins, which have been shown to bind neurexins and heparan sulphate proteoglycan (HSPG) glypican on the presynaptic side. Mutations in the genes encoding LRRTMs and neurexins are im...

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Autores principales: Pavel Uvarov, Tommi Kajander, Matti S Airaksinen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/135a537a56984ac7bd7bfebc8f8f5a33
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