Origin and loss of nested LRRTM/α-catenin genes during vertebrate evolution.

Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) form in mammals a family of four postsynaptic adhesion proteins, which have been shown to bind neurexins and heparan sulphate proteoglycan (HSPG) glypican on the presynaptic side. Mutations in the genes encoding LRRTMs and neurexins are im...

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Auteurs principaux: Pavel Uvarov, Tommi Kajander, Matti S Airaksinen
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/135a537a56984ac7bd7bfebc8f8f5a33
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