Label-free concurrent 5-modal microscopy (Co5M) resolves unknown spatio-temporal processes in wound healing

Seeger et al. demonstrate concurrent 5-modal microscopy (Co5M), combining optoacoustic, two-photon, second and third harmonic generation, and brightfield microscopy in one system. Longitudinal changes associated with the wound healing process in mouse ears were monitored label-free in vivo using com...

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Autores principales:	Markus Seeger, Christoph Dehner, Dominik Jüstel, Vasilis Ntziachristos
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/135b0935ec5a451087587e4c96f0b2f6
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spelling	oai:doaj.org-article:135b0935ec5a451087587e4c96f0b2f62021-12-02T17:41:16ZLabel-free concurrent 5-modal microscopy (Co5M) resolves unknown spatio-temporal processes in wound healing10.1038/s42003-021-02573-52399-3642https://doaj.org/article/135b0935ec5a451087587e4c96f0b2f62021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02573-5https://doaj.org/toc/2399-3642Seeger et al. demonstrate concurrent 5-modal microscopy (Co5M), combining optoacoustic, two-photon, second and third harmonic generation, and brightfield microscopy in one system. Longitudinal changes associated with the wound healing process in mouse ears were monitored label-free in vivo using complementary information obtained from the Co5M system to characterize wound shape, microvascular and collagen density, vessel size and fractality, and the plasticity of sebaceous glands.Markus SeegerChristoph DehnerDominik JüstelVasilis NtziachristosNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Markus Seeger Christoph Dehner Dominik Jüstel Vasilis Ntziachristos Label-free concurrent 5-modal microscopy (Co5M) resolves unknown spatio-temporal processes in wound healing
description	Seeger et al. demonstrate concurrent 5-modal microscopy (Co5M), combining optoacoustic, two-photon, second and third harmonic generation, and brightfield microscopy in one system. Longitudinal changes associated with the wound healing process in mouse ears were monitored label-free in vivo using complementary information obtained from the Co5M system to characterize wound shape, microvascular and collagen density, vessel size and fractality, and the plasticity of sebaceous glands.
format	article
author	Markus Seeger Christoph Dehner Dominik Jüstel Vasilis Ntziachristos
author_facet	Markus Seeger Christoph Dehner Dominik Jüstel Vasilis Ntziachristos
author_sort	Markus Seeger
title	Label-free concurrent 5-modal microscopy (Co5M) resolves unknown spatio-temporal processes in wound healing
title_short	Label-free concurrent 5-modal microscopy (Co5M) resolves unknown spatio-temporal processes in wound healing
title_full	Label-free concurrent 5-modal microscopy (Co5M) resolves unknown spatio-temporal processes in wound healing
title_fullStr	Label-free concurrent 5-modal microscopy (Co5M) resolves unknown spatio-temporal processes in wound healing
title_full_unstemmed	Label-free concurrent 5-modal microscopy (Co5M) resolves unknown spatio-temporal processes in wound healing
title_sort	label-free concurrent 5-modal microscopy (co5m) resolves unknown spatio-temporal processes in wound healing
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/135b0935ec5a451087587e4c96f0b2f6
work_keys_str_mv	AT markusseeger labelfreeconcurrent5modalmicroscopyco5mresolvesunknownspatiotemporalprocessesinwoundhealing AT christophdehner labelfreeconcurrent5modalmicroscopyco5mresolvesunknownspatiotemporalprocessesinwoundhealing AT dominikjustel labelfreeconcurrent5modalmicroscopyco5mresolvesunknownspatiotemporalprocessesinwoundhealing AT vasilisntziachristos labelfreeconcurrent5modalmicroscopyco5mresolvesunknownspatiotemporalprocessesinwoundhealing
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Label-free concurrent 5-modal microscopy (Co5M) resolves unknown spatio-temporal processes in wound healing

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