RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure
Adenosine deaminase acting on RNA 1 (ADAR1) edits adenosine to inosine. Here the authors, using parallel analysis of RNA secondary structure sequencing, provide evidence that ADAR1 induces sequence-context-dependent RNA secondary structures changes, often leading to stabilization of the RNA duplex.
Guardado en:
Autores principales: | Oz Solomon, Ayelet Di Segni, Karen Cesarkas, Hagit T. Porath, Victoria Marcu-Malina, Orel Mizrahi, Noam Stern-Ginossar, Nitzan Kol, Sarit Farage-Barhom, Efrat Glick-Saar, Yaniv Lerenthal, Erez Y. Levanon, Ninette Amariglio, Ron Unger, Itamar Goldstein, Eran Eyal, Gidi Rechavi |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/135bc3a86dbd4e62a8694058deaacfb0 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Fecal microbial characterization of hospitalized patients with suspected infectious diarrhea shows significant dysbiosis
por: Tzipi Braun, et al.
Publicado: (2017) -
Deciphering the Biological Significance of ADAR1–Z-RNA Interactions
por: Taisuke Nakahama, et al.
Publicado: (2021) -
ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair
por: Sonia Jimeno, et al.
Publicado: (2021) -
ADAR1-mediated RNA-editing of 3′UTRs in breast cancer
por: Sagredo,Eduardo A., et al.
Publicado: (2018) -
RNA editing is abundant and correlates with task performance in a social bumblebee
por: Hagit T. Porath, et al.
Publicado: (2019)