EARLY VS LATE CAFFEINE THERAPY IN PRETERM INFANTS: ANALYSIS OF CLINICAL OUTCOME

Objective: To study clinical outcome of early versus late caffeine therapy in preterm infants. Study Design: Prospective comparative study. Place and Duration of Study: Neonatal Intensive Care Unit, Pak Emirates Military Hospital, Rawalpindi, from Jan to Jul 2018. Methodology: A total of 40...

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Autores principales:	Hafsa Niaz, Jawad Jalil, Muhammad Adil, Faisal Basheer, Shahzad Akhtar, Naila Hamid
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2021
Materias:	caffeine therapy neonatal intensive care unit preterm infants Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/136a22eafb1644c7801c632f48abc782
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spelling	oai:doaj.org-article:136a22eafb1644c7801c632f48abc7822021-12-02T18:01:39ZEARLY VS LATE CAFFEINE THERAPY IN PRETERM INFANTS: ANALYSIS OF CLINICAL OUTCOME0030-96482411-884210.51253/pafmj.v71i2.3769https://doaj.org/article/136a22eafb1644c7801c632f48abc7822021-04-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/3769https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To study clinical outcome of early versus late caffeine therapy in preterm infants. Study Design: Prospective comparative study. Place and Duration of Study: Neonatal Intensive Care Unit, Pak Emirates Military Hospital, Rawalpindi, from Jan to Jul 2018. Methodology: A total of 40 preterm infants with gestational age <32 weeks and birth weight <1500 grams were randomly divided into two groups on the basis of initiation of caffeine therapy i.e. group A (early caffeine group) and group B (late caffeine group). Infant’s demographic data and clinical outcomes were compared between both groups using SPSS IBM software. Results: Mean gestational age was 29.9 ± 1.19 weeks with male to female ratio of 1.5:1 Mean birth weight was 1165.3 ± 316 grams. Half (50%) of the infants were delivered by cesarean section while surfactant was given in 29 (72.5%) infants. While comparing both groups we observed that early caffeine shortens duration of Neonatal Intensive Care Unit stay (p<0.05) whereas caffeine therapy initiation timings didn’t influence the risk of development of Respiratory Distress Syndrome or need of mechanical ventilation. Conclusion: Early caffeine therapy in preterm infants is associated with decrease duration of Neonatal Intensive Care Unit stay. However further work is needed in this regards to establish its efficacy and safety.Hafsa NiazJawad JalilMuhammad AdilFaisal BasheerShahzad AkhtarNaila HamidArmy Medical College Rawalpindiarticlecaffeine therapyneonatal intensive care unitpreterm infantsMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 71, Iss 2, Pp 503-06 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	caffeine therapy neonatal intensive care unit preterm infants Medicine R Medicine (General) R5-920
spellingShingle	caffeine therapy neonatal intensive care unit preterm infants Medicine R Medicine (General) R5-920 Hafsa Niaz Jawad Jalil Muhammad Adil Faisal Basheer Shahzad Akhtar Naila Hamid EARLY VS LATE CAFFEINE THERAPY IN PRETERM INFANTS: ANALYSIS OF CLINICAL OUTCOME
description	Objective: To study clinical outcome of early versus late caffeine therapy in preterm infants. Study Design: Prospective comparative study. Place and Duration of Study: Neonatal Intensive Care Unit, Pak Emirates Military Hospital, Rawalpindi, from Jan to Jul 2018. Methodology: A total of 40 preterm infants with gestational age <32 weeks and birth weight <1500 grams were randomly divided into two groups on the basis of initiation of caffeine therapy i.e. group A (early caffeine group) and group B (late caffeine group). Infant’s demographic data and clinical outcomes were compared between both groups using SPSS IBM software. Results: Mean gestational age was 29.9 ± 1.19 weeks with male to female ratio of 1.5:1 Mean birth weight was 1165.3 ± 316 grams. Half (50%) of the infants were delivered by cesarean section while surfactant was given in 29 (72.5%) infants. While comparing both groups we observed that early caffeine shortens duration of Neonatal Intensive Care Unit stay (p<0.05) whereas caffeine therapy initiation timings didn’t influence the risk of development of Respiratory Distress Syndrome or need of mechanical ventilation. Conclusion: Early caffeine therapy in preterm infants is associated with decrease duration of Neonatal Intensive Care Unit stay. However further work is needed in this regards to establish its efficacy and safety.
format	article
author	Hafsa Niaz Jawad Jalil Muhammad Adil Faisal Basheer Shahzad Akhtar Naila Hamid
author_facet	Hafsa Niaz Jawad Jalil Muhammad Adil Faisal Basheer Shahzad Akhtar Naila Hamid
author_sort	Hafsa Niaz
title	EARLY VS LATE CAFFEINE THERAPY IN PRETERM INFANTS: ANALYSIS OF CLINICAL OUTCOME
title_short	EARLY VS LATE CAFFEINE THERAPY IN PRETERM INFANTS: ANALYSIS OF CLINICAL OUTCOME
title_full	EARLY VS LATE CAFFEINE THERAPY IN PRETERM INFANTS: ANALYSIS OF CLINICAL OUTCOME
title_fullStr	EARLY VS LATE CAFFEINE THERAPY IN PRETERM INFANTS: ANALYSIS OF CLINICAL OUTCOME
title_full_unstemmed	EARLY VS LATE CAFFEINE THERAPY IN PRETERM INFANTS: ANALYSIS OF CLINICAL OUTCOME
title_sort	early vs late caffeine therapy in preterm infants: analysis of clinical outcome
publisher	Army Medical College Rawalpindi
publishDate	2021
url	https://doaj.org/article/136a22eafb1644c7801c632f48abc782
work_keys_str_mv	AT hafsaniaz earlyvslatecaffeinetherapyinpreterminfantsanalysisofclinicaloutcome AT jawadjalil earlyvslatecaffeinetherapyinpreterminfantsanalysisofclinicaloutcome AT muhammadadil earlyvslatecaffeinetherapyinpreterminfantsanalysisofclinicaloutcome AT faisalbasheer earlyvslatecaffeinetherapyinpreterminfantsanalysisofclinicaloutcome AT shahzadakhtar earlyvslatecaffeinetherapyinpreterminfantsanalysisofclinicaloutcome AT nailahamid earlyvslatecaffeinetherapyinpreterminfantsanalysisofclinicaloutcome
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EARLY VS LATE CAFFEINE THERAPY IN PRETERM INFANTS: ANALYSIS OF CLINICAL OUTCOME

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