Insight in Leptin Gene Polymorphism and Impact on Milk Traits in Autochtonous Busha Cattle

Leptin, a biomolecule secreted by adipose tissue, enchances productivity in cattle, especially affecting milk traits. The aim of this study was to detect leptin gene polymorphism on exon 3 (A59V locus) and intron 2 (SAU3AI locus) in the endangered population of autochtonous Busha cattle and associat...

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Autores principales:	Maletić Milan, Paprikić Nevres, Lazarević Miodrag, Hodžić Aida, Davidović Vesna, Stanišić Ljubodrag, Stanimirović Zoran
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2019
Materias:	busha cattle leptin polymorphsm milk traits genetic markers Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/136cfc2022634750879c6b914f795b84
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id	oai:doaj.org-article:136cfc2022634750879c6b914f795b84
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spelling	oai:doaj.org-article:136cfc2022634750879c6b914f795b842021-11-17T21:27:53ZInsight in Leptin Gene Polymorphism and Impact on Milk Traits in Autochtonous Busha Cattle1820-744810.2478/acve-2019-0012https://doaj.org/article/136cfc2022634750879c6b914f795b842019-06-01T00:00:00Zhttps://doi.org/10.2478/acve-2019-0012https://doaj.org/toc/1820-7448Leptin, a biomolecule secreted by adipose tissue, enchances productivity in cattle, especially affecting milk traits. The aim of this study was to detect leptin gene polymorphism on exon 3 (A59V locus) and intron 2 (SAU3AI locus) in the endangered population of autochtonous Busha cattle and associations with milk traits. The study included 46 cows: 36 Busha and 10 half-bred. Milk analyses comprised determination of somatic cell counts, fat, protein, lactose, total solids and solids-not-fat (SNF) concentrations and freezing point depression (FPD). Polymorphisms were determined by PCR-RFLP technique. A single A59V genotype (CC) was affirmed, and two SAU3AI genotypes, AA and AB, with frequencies of 78.26% and 21.74%, respectively. Comparing the obtained results for chemical characteristics of milk between cows with AA and AB, no significant differences were found, except for SNF content and FPD values. Cows with AA genotype had significantly lower (p=0.021) average SNF content (8.74%) in milk compared to the average SNF content (9.28%) in those with genotype AB, while cows with genotype AA (−0.54°C) had significantly higher (p=0.004) average FPD values than those with AB genotype (−0.58°C). The absence of BB genotype and significant differences in the investigated functional traits between two SAU3AI genotypes and the absence of A59V polymorphism (presence of only CC genotype) show that the Busha cattle breed, although being an autochtonous low-producing native breed used for meat and milk production, harbours polymorphism on gentic markers characteristic of high production dairy cows.Maletić MilanPaprikić NevresLazarević MiodragHodžić AidaDavidović VesnaStanišić LjubodragStanimirović ZoranSciendoarticlebusha cattleleptin polymorphsmmilk traitsgenetic markersVeterinary medicineSF600-1100ENActa Veterinaria, Vol 69, Iss 2, Pp 153-163 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	busha cattle leptin polymorphsm milk traits genetic markers Veterinary medicine SF600-1100
spellingShingle	busha cattle leptin polymorphsm milk traits genetic markers Veterinary medicine SF600-1100 Maletić Milan Paprikić Nevres Lazarević Miodrag Hodžić Aida Davidović Vesna Stanišić Ljubodrag Stanimirović Zoran Insight in Leptin Gene Polymorphism and Impact on Milk Traits in Autochtonous Busha Cattle
description	Leptin, a biomolecule secreted by adipose tissue, enchances productivity in cattle, especially affecting milk traits. The aim of this study was to detect leptin gene polymorphism on exon 3 (A59V locus) and intron 2 (SAU3AI locus) in the endangered population of autochtonous Busha cattle and associations with milk traits. The study included 46 cows: 36 Busha and 10 half-bred. Milk analyses comprised determination of somatic cell counts, fat, protein, lactose, total solids and solids-not-fat (SNF) concentrations and freezing point depression (FPD). Polymorphisms were determined by PCR-RFLP technique. A single A59V genotype (CC) was affirmed, and two SAU3AI genotypes, AA and AB, with frequencies of 78.26% and 21.74%, respectively. Comparing the obtained results for chemical characteristics of milk between cows with AA and AB, no significant differences were found, except for SNF content and FPD values. Cows with AA genotype had significantly lower (p=0.021) average SNF content (8.74%) in milk compared to the average SNF content (9.28%) in those with genotype AB, while cows with genotype AA (−0.54°C) had significantly higher (p=0.004) average FPD values than those with AB genotype (−0.58°C). The absence of BB genotype and significant differences in the investigated functional traits between two SAU3AI genotypes and the absence of A59V polymorphism (presence of only CC genotype) show that the Busha cattle breed, although being an autochtonous low-producing native breed used for meat and milk production, harbours polymorphism on gentic markers characteristic of high production dairy cows.
format	article
author	Maletić Milan Paprikić Nevres Lazarević Miodrag Hodžić Aida Davidović Vesna Stanišić Ljubodrag Stanimirović Zoran
author_facet	Maletić Milan Paprikić Nevres Lazarević Miodrag Hodžić Aida Davidović Vesna Stanišić Ljubodrag Stanimirović Zoran
author_sort	Maletić Milan
title	Insight in Leptin Gene Polymorphism and Impact on Milk Traits in Autochtonous Busha Cattle
title_short	Insight in Leptin Gene Polymorphism and Impact on Milk Traits in Autochtonous Busha Cattle
title_full	Insight in Leptin Gene Polymorphism and Impact on Milk Traits in Autochtonous Busha Cattle
title_fullStr	Insight in Leptin Gene Polymorphism and Impact on Milk Traits in Autochtonous Busha Cattle
title_full_unstemmed	Insight in Leptin Gene Polymorphism and Impact on Milk Traits in Autochtonous Busha Cattle
title_sort	insight in leptin gene polymorphism and impact on milk traits in autochtonous busha cattle
publisher	Sciendo
publishDate	2019
url	https://doaj.org/article/136cfc2022634750879c6b914f795b84
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Insight in Leptin Gene Polymorphism and Impact on Milk Traits in Autochtonous Busha Cattle

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