Hypoglycemia due to an adult-onset nesidioblastosis, a diagnostic and management dilemma
We describe a case of a 40 year old patient with recurrent severe fasting and postprandial symptomatic hypoglycemia that occurred 6 years after gastric bypass surgery. The hypoglycemia was associated with increased insulin and C peptide but all diagnostic modalities for localizing an insulinoma were...
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2012
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oai:doaj.org-article:137c3fc8f1bd47e4a1a2abf3e914605c2021-12-02T16:24:51ZHypoglycemia due to an adult-onset nesidioblastosis, a diagnostic and management dilemma2231-07702249-446410.4103/2231-0770.99164https://doaj.org/article/137c3fc8f1bd47e4a1a2abf3e914605c2012-04-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/2231-0770.99164https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464We describe a case of a 40 year old patient with recurrent severe fasting and postprandial symptomatic hypoglycemia that occurred 6 years after gastric bypass surgery. The hypoglycemia was associated with increased insulin and C peptide but all diagnostic modalities for localizing an insulinoma were negative. Medical management failed to control symptoms and the patient underwent subtotal pancreatectomy. Surgical tissue examination confirmed the diagnosis of noninsulinoma pancreatogenous hypoglycaemia syndrome (NIPHS) or nesidioblastosis. Initially after surgery the patient had full remission but after 6 months hypoglycemia recurred. However, this time it was well-controlled with octreotide treatment.Mohammed QintarFiras SibaiMohammad TahaThieme Medical and Scientific Publishers Pvt. Ltd.articlehypoglycemianesidioblastosisgastric bypass surgerynoninsulinoma pancreatogenous hypoglycaemia syndromeniphsMedicineRENAvicenna Journal of Medicine, Vol 02, Iss 02, Pp 45-47 (2012) |
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hypoglycemia nesidioblastosis gastric bypass surgery noninsulinoma pancreatogenous hypoglycaemia syndrome niphs Medicine R |
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hypoglycemia nesidioblastosis gastric bypass surgery noninsulinoma pancreatogenous hypoglycaemia syndrome niphs Medicine R Mohammed Qintar Firas Sibai Mohammad Taha Hypoglycemia due to an adult-onset nesidioblastosis, a diagnostic and management dilemma |
description |
We describe a case of a 40 year old patient with recurrent severe fasting and postprandial symptomatic hypoglycemia that occurred 6 years after gastric bypass surgery. The hypoglycemia was associated with increased insulin and C peptide but all diagnostic modalities for localizing an insulinoma were negative. Medical management failed to control symptoms and the patient underwent subtotal pancreatectomy. Surgical tissue examination confirmed the diagnosis of noninsulinoma pancreatogenous hypoglycaemia syndrome (NIPHS) or nesidioblastosis. Initially after surgery the patient had full remission but after 6 months hypoglycemia recurred. However, this time it was well-controlled with octreotide treatment. |
format |
article |
author |
Mohammed Qintar Firas Sibai Mohammad Taha |
author_facet |
Mohammed Qintar Firas Sibai Mohammad Taha |
author_sort |
Mohammed Qintar |
title |
Hypoglycemia due to an adult-onset nesidioblastosis, a diagnostic and management dilemma |
title_short |
Hypoglycemia due to an adult-onset nesidioblastosis, a diagnostic and management dilemma |
title_full |
Hypoglycemia due to an adult-onset nesidioblastosis, a diagnostic and management dilemma |
title_fullStr |
Hypoglycemia due to an adult-onset nesidioblastosis, a diagnostic and management dilemma |
title_full_unstemmed |
Hypoglycemia due to an adult-onset nesidioblastosis, a diagnostic and management dilemma |
title_sort |
hypoglycemia due to an adult-onset nesidioblastosis, a diagnostic and management dilemma |
publisher |
Thieme Medical and Scientific Publishers Pvt. Ltd. |
publishDate |
2012 |
url |
https://doaj.org/article/137c3fc8f1bd47e4a1a2abf3e914605c |
work_keys_str_mv |
AT mohammedqintar hypoglycemiaduetoanadultonsetnesidioblastosisadiagnosticandmanagementdilemma AT firassibai hypoglycemiaduetoanadultonsetnesidioblastosisadiagnosticandmanagementdilemma AT mohammadtaha hypoglycemiaduetoanadultonsetnesidioblastosisadiagnosticandmanagementdilemma |
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1718384096027082752 |