ANTISEPTICS AT INTRAVITREAL INJECTIONS

Authors analyze efficiency of application antiseptics of a miramistin in prevention of infectious complications in case of repeated intravitreal injections of VEGF inhibitor Ranibizumab in 156 patients with the age related macular degeneration. 0,01% solution of antiseptic Miramistin (Okomistin®) wa...

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Autores principales:	I. E. Ioshin, A. I. Tolchinskaya, A. A. Ozderbayeva
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:	intravitreal injections endophthalmitis prevention Science Q
Acceso en línea:	https://doaj.org/article/1380bbe88b344a19bc1025ad50d42d47
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spelling	oai:doaj.org-article:1380bbe88b344a19bc1025ad50d42d472021-11-23T06:14:36ZANTISEPTICS AT INTRAVITREAL INJECTIONS2541-94202587-959610.12737/23735https://doaj.org/article/1380bbe88b344a19bc1025ad50d42d472016-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/320https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Authors analyze efficiency of application antiseptics of a miramistin in prevention of infectious complications in case of repeated intravitreal injections of VEGF inhibitor Ranibizumab in 156 patients with the age related macular degeneration. 0,01% solution of antiseptic Miramistin (Okomistin®) was instillated 4 times per day two days before operation to all patients for the purpose of infection prevention. Just before the operation (60 and 30 minutes before) and right after it instillations of antiseptic continued within a week after intravitreal injection. During the operation in the conditions of the operating room with keeping of all rules of aseptic, three minutes prior to operation the surgery field and the conjunctival cavity of the patient were twice processed by 5% povidone-iodine solution (Betadine). The results analysis showed no expressed signs of irritation of the eyes connected to miramistin treatment preceding the operation. In the postoperative period all patients endured antiseptics well. Within a week of applications there were no complaints about pain, burning, foreign body sensation or hazy vision after the medicine instillation, and biomicroscopic research revealed no signs of inflammatory injection of conjunctiva or sclera, no cornea epitheliopathy, there was no cellular response in moisture of the anterior chamber and vitreous body. Thus, the authors state that antiseptics Okomistin® as an additional measure of prevention of infectious complications in case ofintravitreal injection provide high level antimicrobic protection with no risk of development of microbial resistance.I. E. IoshinA. I. TolchinskayaA. A. OzderbayevaScientific Сentre for Family Health and Human Reproduction Problemsarticleintravitreal injectionsendophthalmitispreventionScienceQRUActa Biomedica Scientifica, Vol 1, Iss 6, Pp 55-59 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	intravitreal injections endophthalmitis prevention Science Q
spellingShingle	intravitreal injections endophthalmitis prevention Science Q I. E. Ioshin A. I. Tolchinskaya A. A. Ozderbayeva ANTISEPTICS AT INTRAVITREAL INJECTIONS
description	Authors analyze efficiency of application antiseptics of a miramistin in prevention of infectious complications in case of repeated intravitreal injections of VEGF inhibitor Ranibizumab in 156 patients with the age related macular degeneration. 0,01% solution of antiseptic Miramistin (Okomistin®) was instillated 4 times per day two days before operation to all patients for the purpose of infection prevention. Just before the operation (60 and 30 minutes before) and right after it instillations of antiseptic continued within a week after intravitreal injection. During the operation in the conditions of the operating room with keeping of all rules of aseptic, three minutes prior to operation the surgery field and the conjunctival cavity of the patient were twice processed by 5% povidone-iodine solution (Betadine). The results analysis showed no expressed signs of irritation of the eyes connected to miramistin treatment preceding the operation. In the postoperative period all patients endured antiseptics well. Within a week of applications there were no complaints about pain, burning, foreign body sensation or hazy vision after the medicine instillation, and biomicroscopic research revealed no signs of inflammatory injection of conjunctiva or sclera, no cornea epitheliopathy, there was no cellular response in moisture of the anterior chamber and vitreous body. Thus, the authors state that antiseptics Okomistin® as an additional measure of prevention of infectious complications in case ofintravitreal injection provide high level antimicrobic protection with no risk of development of microbial resistance.
format	article
author	I. E. Ioshin A. I. Tolchinskaya A. A. Ozderbayeva
author_facet	I. E. Ioshin A. I. Tolchinskaya A. A. Ozderbayeva
author_sort	I. E. Ioshin
title	ANTISEPTICS AT INTRAVITREAL INJECTIONS
title_short	ANTISEPTICS AT INTRAVITREAL INJECTIONS
title_full	ANTISEPTICS AT INTRAVITREAL INJECTIONS
title_fullStr	ANTISEPTICS AT INTRAVITREAL INJECTIONS
title_full_unstemmed	ANTISEPTICS AT INTRAVITREAL INJECTIONS
title_sort	antiseptics at intravitreal injections
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2016
url	https://doaj.org/article/1380bbe88b344a19bc1025ad50d42d47
work_keys_str_mv	AT ieioshin antisepticsatintravitrealinjections AT aitolchinskaya antisepticsatintravitrealinjections AT aaozderbayeva antisepticsatintravitrealinjections
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ANTISEPTICS AT INTRAVITREAL INJECTIONS

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