Molecular resolution imaging by post-labeling expansion single-molecule localization microscopy (Ex-SMLM)

Molecular resolution imaging by post-labeling expansion single-molecule localization microscopy (Ex-SMLM)

Previous attempts to combine expansion microscopy (ExM) and single molecule localisation microscopy (SMLM) have proved challenging. Here the authors show that post-labelling Ex-SMLM improves labelling efficiency, reduces linkage error, and preserves ultrastructural details.

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Detalles Bibliográficos
Autores principales: Fabian U. Zwettler, Sebastian Reinhard, Davide Gambarotto, Toby D. M. Bell, Virginie Hamel, Paul Guichard, Markus Sauer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
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Acceso en línea:https://doaj.org/article/138518bbdfb845248b9023cf52af2865
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