Rapid erasure of hippocampal memory following inhibition of dentate gyrus granule cells
Dentate gyrus (DG) is critical for memory formation in the hippocampus but its role in memory retrieval is unclear. Here, Gross and colleagues, show that granule cells in DG are not required for memory retrieval but for maintenance, and inhibiting them with a drug leads to rapid loss of memory.
Guardado en:
Autores principales: | Noelia Madroñal, José M. Delgado-García, Azahara Fernández-Guizán, Jayanta Chatterjee, Maja Köhn, Camilla Mattucci, Apar Jain, Theodoros Tsetsenis, Anna Illarionova, Valery Grinevich, Cornelius T. Gross, Agnès Gruart |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
|
Materias: | |
Acceso en línea: | https://doaj.org/article/13901a51755d460bbbcc7c6b45385d81 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Dendritic inhibition differentially regulates excitability of dentate gyrus parvalbumin-expressing interneurons and granule cells
por: Claudio Elgueta, et al.
Publicado: (2019) -
Dietary polyphenols enhance optogenetic recall of fear memory in hippocampal dentate gyrus granule neuron subpopulations
por: Chad Smith, et al.
Publicado: (2018) -
Late maturation of adult-born neurons in the temporal dentate gyrus.
por: Jason S Snyder, et al.
Publicado: (2012) -
How informative are spatial CA3 representations established by the dentate gyrus?
por: Erika Cerasti, et al.
Publicado: (2010) -
Distance-dependent inhibition facilitates focality of gamma oscillations in the dentate gyrus
por: Michael Strüber, et al.
Publicado: (2017)