PADI4 and HLA-DRB1 are genetic risks for radiographic progression in RA patients, independent of ACPA status: results from the IORRA cohort study.
<h4>Introduction</h4>Rheumatoid arthritis (RA) is a systemic, chronic inflammatory disease influenced by both genetic and environmental factors, leading to joint destruction and functional impairment. Recently, a large-scaled GWAS meta-analysis using more than 37,000 Japanese samples wer...
Guardado en:
Autores principales: | Taku Suzuki, Katsunori Ikari, Koichiro Yano, Eisuke Inoue, Yoshiaki Toyama, Atsuo Taniguchi, Hisashi Yamanaka, Shigeki Momohara |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
|
Materias: | |
Acceso en línea: | https://doaj.org/article/139c2268de32448cb41376978801695d |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
HLA-DRB1 genotypes and the risk of developing anti citrullinated protein antibody (ACPA) positive rheumatoid arthritis.
por: Nathalie Balandraud, et al.
Publicado: (2013) -
Time-averaged disease activity fits better joint destruction in rheumatoid arthritis
por: Hideaki Tsuji, et al.
Publicado: (2017) -
Anti-centromere antibody exhibits specific distribution levels among anti-nuclear antibodies and may characterize a distinct subset in rheumatoid arthritis
por: Nobuo Kuramoto, et al.
Publicado: (2017) - RAED Journal / RAED Dergisi
-
Citrullination of pyruvate kinase M2 by PADI1 and PADI3 regulates glycolysis and cancer cell proliferation
por: Sébastien Coassolo, et al.
Publicado: (2021)