Inflammasome activation negatively regulates MyD88-IRF7 type I IFN signaling and anti-malaria immunity

Inflammasome activation negatively regulates MyD88-IRF7 type I IFN signaling and anti-malaria immunity

The inflammasome is an essential component of inflammatory processes and the host response to infection. Here the authors show that inflammasome activation modulates MyD88-IRF7 type I IFN signalling and anti-malaria immunity.

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Bibliographic Details
Main Authors: Xiao Yu, Yang Du, Chunmei Cai, Baowei Cai, Motao Zhu, Changsheng Xing, Peng Tan, Meng Lin, Jian Wu, Jian Li, Mingjun Wang, Helen Y. Wang, Xin-zhuan Su, Rong-Fu Wang
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Science
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Online Access:https://doaj.org/article/139d3e3e79e44205a9c09f58cb4163c5
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Summary:The inflammasome is an essential component of inflammatory processes and the host response to infection. Here the authors show that inflammasome activation modulates MyD88-IRF7 type I IFN signalling and anti-malaria immunity.

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