CB1R activation in nucleus accumbens core promotes stress-induced reinstatement of cocaine seeking by elevating extracellular glutamate in a drug-paired context

Abstract Preclinical models of stress-induced relapse to drug use have shown that the dysregulation of glutamatergic transmission within the nucleus accumbens (NA) contributes notably to the reinstatement of cocaine-seeking behavior in rodents. In this sense, there has been increasing interest in th...

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Autores principales: Andrea S. Guzman, Maria P. Avalos, Laura N. De Giovanni, Pia V. Euliarte, Marianela A. Sanchez, Bethania Mongi-Bragato, Daiana Rigoni, Flavia A. Bollati, Miriam B. Virgolini, Liliana M. Cancela
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/13aa329ce9d141d69ba00d3f8c8c4487
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