Approximate conditional phenotype analysis based on genome wide association summary statistics

Approximate conditional phenotype analysis based on genome wide association summary statistics

Abstract Because single genetic variants may have pleiotropic effects, one trait can be a confounder in a genome-wide association study (GWAS) that aims to identify loci associated with another trait. A typical approach to address this issue is to perform an additional analysis adjusting for the con...

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Autores principales: Peitao Wu, Biqi Wang, Steven A. Lubitz, Emelia J. Benjamin, James B. Meigs, Josée Dupuis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/13ad1023b2e04c5caf175a7085c14354
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