Peptidoglycan reshaping by a noncanonical peptidase for helical cell shape in Campylobacter jejuni

Peptidoglycans (PG) define bacterial cell shapes. Here, the authors provide mechanistic insights into the peptidoglycan peptidase 3 (Pgp3) from the spiral shaped human pathogen Campylobacter jejuni by determining its crystal structure alone and in complex with synthetic cell-wall PG derivatives, and...

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Autores principales:	Kyungjin Min, Doo Ri An, Hye-Jin Yoon, Neha Rana, Ji Su Park, Jinshil Kim, Mijoon Lee, Dusan Hesek, Sangryeol Ryu, B. Moon Kim, Shahriar Mobashery, Se Won Suh, Hyung Ho Lee
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/13c1a77948d7413ba83fdcf089e8a278
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spelling	oai:doaj.org-article:13c1a77948d7413ba83fdcf089e8a2782021-12-02T15:34:36ZPeptidoglycan reshaping by a noncanonical peptidase for helical cell shape in Campylobacter jejuni10.1038/s41467-019-13934-42041-1723https://doaj.org/article/13c1a77948d7413ba83fdcf089e8a2782020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13934-4https://doaj.org/toc/2041-1723Peptidoglycans (PG) define bacterial cell shapes. Here, the authors provide mechanistic insights into the peptidoglycan peptidase 3 (Pgp3) from the spiral shaped human pathogen Campylobacter jejuni by determining its crystal structure alone and in complex with synthetic cell-wall PG derivatives, and they further show that the enzyme has both d,d-endopeptidase and d,d-carboxypeptidase activitiesKyungjin MinDoo Ri AnHye-Jin YoonNeha RanaJi Su ParkJinshil KimMijoon LeeDusan HesekSangryeol RyuB. Moon KimShahriar MobasherySe Won SuhHyung Ho LeeNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kyungjin Min Doo Ri An Hye-Jin Yoon Neha Rana Ji Su Park Jinshil Kim Mijoon Lee Dusan Hesek Sangryeol Ryu B. Moon Kim Shahriar Mobashery Se Won Suh Hyung Ho Lee Peptidoglycan reshaping by a noncanonical peptidase for helical cell shape in Campylobacter jejuni
description	Peptidoglycans (PG) define bacterial cell shapes. Here, the authors provide mechanistic insights into the peptidoglycan peptidase 3 (Pgp3) from the spiral shaped human pathogen Campylobacter jejuni by determining its crystal structure alone and in complex with synthetic cell-wall PG derivatives, and they further show that the enzyme has both d,d-endopeptidase and d,d-carboxypeptidase activities
format	article
author	Kyungjin Min Doo Ri An Hye-Jin Yoon Neha Rana Ji Su Park Jinshil Kim Mijoon Lee Dusan Hesek Sangryeol Ryu B. Moon Kim Shahriar Mobashery Se Won Suh Hyung Ho Lee
author_facet	Kyungjin Min Doo Ri An Hye-Jin Yoon Neha Rana Ji Su Park Jinshil Kim Mijoon Lee Dusan Hesek Sangryeol Ryu B. Moon Kim Shahriar Mobashery Se Won Suh Hyung Ho Lee
author_sort	Kyungjin Min
title	Peptidoglycan reshaping by a noncanonical peptidase for helical cell shape in Campylobacter jejuni
title_short	Peptidoglycan reshaping by a noncanonical peptidase for helical cell shape in Campylobacter jejuni
title_full	Peptidoglycan reshaping by a noncanonical peptidase for helical cell shape in Campylobacter jejuni
title_fullStr	Peptidoglycan reshaping by a noncanonical peptidase for helical cell shape in Campylobacter jejuni
title_full_unstemmed	Peptidoglycan reshaping by a noncanonical peptidase for helical cell shape in Campylobacter jejuni
title_sort	peptidoglycan reshaping by a noncanonical peptidase for helical cell shape in campylobacter jejuni
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/13c1a77948d7413ba83fdcf089e8a278
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Peptidoglycan reshaping by a noncanonical peptidase for helical cell shape in Campylobacter jejuni

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