Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database

Introduction: Traditional Japanese (Kampo) medicines are often prescribed for women in Japan before, during, and after pregnancy. However, detailed information on the actual frequency of use and safety of Kampo preparations during pregnancy is lacking.Aim: To investigate the frequency of prescriptio...

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Autores principales:	Satoko Suzuki, Taku Obara, Tomofumi Ishikawa, Aoi Noda, Fumiko Matsuzaki, Ryutaro Arita, Minoru Ohsawa, Nariyasu Mano, Akiko Kikuchi, Shin Takayama, Tadashi Ishii
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	herbal medicine Japanese traditional medicine Kampo medicine pregnant women database Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/13c348dd88dd473ab42867f04045f520
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spelling	oai:doaj.org-article:13c348dd88dd473ab42867f04045f5202021-11-12T09:27:29ZPrescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database2296-861X10.3389/fnut.2021.762895https://doaj.org/article/13c348dd88dd473ab42867f04045f5202021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fnut.2021.762895/fullhttps://doaj.org/toc/2296-861XIntroduction: Traditional Japanese (Kampo) medicines are often prescribed for women in Japan before, during, and after pregnancy. However, detailed information on the actual frequency of use and safety of Kampo preparations during pregnancy is lacking.Aim: To investigate the frequency of prescription of Kampo medicines for pregnant women in Japan.Methods: Information on Kampo medicines prescribed during outpatient care and hospitalization of selected mothers from January 2005 to August 2016 were extracted from the Japan Medical Data Center (Tokyo, Japan), which is a large claims database.Results: Of the 33,941 subscribers identified from the database, 16,294 (48%) received at least one prescription of a Kampo medicine. Kakkonto was the formula most prescribed during the study period, followed by shoseiryuto and tokishakuyakusan. In the 180 days before pregnancy, the most prescribed medicine was tokishakuyakusan, followed by kakkonto and shoseiryuto. Shoseiryuto, tokishakuyakusan, and kakkonnto were the formulae most prescribed during pregnancy. The most prescribed medicines during the 180 days postpartum were kakkonto, shoseiryuto, and saireito.Conclusions: Information in the Japanese insurance system shows that Kampo medicines are often prescribed during pregnancy. Most of these prescriptions are generally used for the treatment of common cold. Tokishakuyakusan in particular is usually used in the treatment of various symptoms of pregnancy. Further research is needed to clarify the relationship between the use of Kampo medicines during pregnancy and adverse events in infants in Japan.Satoko SuzukiSatoko SuzukiTaku ObaraTaku ObaraTomofumi IshikawaAoi NodaAoi NodaFumiko MatsuzakiRyutaro AritaRyutaro AritaMinoru OhsawaMinoru OhsawaMinoru OhsawaNariyasu ManoAkiko KikuchiAkiko KikuchiShin TakayamaShin TakayamaTadashi IshiiTadashi IshiiFrontiers Media S.A.articleherbal medicineJapanese traditional medicineKampo medicinepregnant womendatabaseNutrition. Foods and food supplyTX341-641ENFrontiers in Nutrition, Vol 8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	herbal medicine Japanese traditional medicine Kampo medicine pregnant women database Nutrition. Foods and food supply TX341-641
spellingShingle	herbal medicine Japanese traditional medicine Kampo medicine pregnant women database Nutrition. Foods and food supply TX341-641 Satoko Suzuki Satoko Suzuki Taku Obara Taku Obara Tomofumi Ishikawa Aoi Noda Aoi Noda Fumiko Matsuzaki Ryutaro Arita Ryutaro Arita Minoru Ohsawa Minoru Ohsawa Minoru Ohsawa Nariyasu Mano Akiko Kikuchi Akiko Kikuchi Shin Takayama Shin Takayama Tadashi Ishii Tadashi Ishii Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database
description	Introduction: Traditional Japanese (Kampo) medicines are often prescribed for women in Japan before, during, and after pregnancy. However, detailed information on the actual frequency of use and safety of Kampo preparations during pregnancy is lacking.Aim: To investigate the frequency of prescription of Kampo medicines for pregnant women in Japan.Methods: Information on Kampo medicines prescribed during outpatient care and hospitalization of selected mothers from January 2005 to August 2016 were extracted from the Japan Medical Data Center (Tokyo, Japan), which is a large claims database.Results: Of the 33,941 subscribers identified from the database, 16,294 (48%) received at least one prescription of a Kampo medicine. Kakkonto was the formula most prescribed during the study period, followed by shoseiryuto and tokishakuyakusan. In the 180 days before pregnancy, the most prescribed medicine was tokishakuyakusan, followed by kakkonto and shoseiryuto. Shoseiryuto, tokishakuyakusan, and kakkonnto were the formulae most prescribed during pregnancy. The most prescribed medicines during the 180 days postpartum were kakkonto, shoseiryuto, and saireito.Conclusions: Information in the Japanese insurance system shows that Kampo medicines are often prescribed during pregnancy. Most of these prescriptions are generally used for the treatment of common cold. Tokishakuyakusan in particular is usually used in the treatment of various symptoms of pregnancy. Further research is needed to clarify the relationship between the use of Kampo medicines during pregnancy and adverse events in infants in Japan.
format	article
author	Satoko Suzuki Satoko Suzuki Taku Obara Taku Obara Tomofumi Ishikawa Aoi Noda Aoi Noda Fumiko Matsuzaki Ryutaro Arita Ryutaro Arita Minoru Ohsawa Minoru Ohsawa Minoru Ohsawa Nariyasu Mano Akiko Kikuchi Akiko Kikuchi Shin Takayama Shin Takayama Tadashi Ishii Tadashi Ishii
author_facet	Satoko Suzuki Satoko Suzuki Taku Obara Taku Obara Tomofumi Ishikawa Aoi Noda Aoi Noda Fumiko Matsuzaki Ryutaro Arita Ryutaro Arita Minoru Ohsawa Minoru Ohsawa Minoru Ohsawa Nariyasu Mano Akiko Kikuchi Akiko Kikuchi Shin Takayama Shin Takayama Tadashi Ishii Tadashi Ishii
author_sort	Satoko Suzuki
title	Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database
title_short	Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database
title_full	Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database
title_fullStr	Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database
title_full_unstemmed	Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database
title_sort	prescription of kampo formulations for pre-natal and post-partum women in japan: data from an administrative health database
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/13c348dd88dd473ab42867f04045f520
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Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database

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